Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is an orphan disease characterized by progressive loss of lung function resulting in shortness of breath and often death within 3–4 years of diagnosis. Repetitive lung injury in susceptible individuals is believed to promote chronic oxidative stress,...

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Autores principales: Ebrahimpour, Afshin, Wang, Min, Li, Li, Jegga, Anil G., Bonnen, Mark D., Eissa, N. Tony, Raghu, Ganesh, Jyothula, Soma, Kheradmand, Farrah, Hanania, Nicola A., Rosas, Ivan O., Ghebre, Yohannes T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136131/
https://www.ncbi.nlm.nih.gov/pubmed/34011367
http://dx.doi.org/10.1186/s12950-021-00284-6

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