A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal

Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical...

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Autores principales: Cordes Selby, Susan, Iwata‐Otsubo, Aiko, Delk, Paula, Nebesio, Todd D., Gohil, Anisha, Matlock, Peggy, Torres‐Martinez, Wilfredo, Vance, Gail H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136447/
https://www.ncbi.nlm.nih.gov/pubmed/34026173
http://dx.doi.org/10.1002/ccr3.4141
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author Cordes Selby, Susan
Iwata‐Otsubo, Aiko
Delk, Paula
Nebesio, Todd D.
Gohil, Anisha
Matlock, Peggy
Torres‐Martinez, Wilfredo
Vance, Gail H.
author_facet Cordes Selby, Susan
Iwata‐Otsubo, Aiko
Delk, Paula
Nebesio, Todd D.
Gohil, Anisha
Matlock, Peggy
Torres‐Martinez, Wilfredo
Vance, Gail H.
author_sort Cordes Selby, Susan
collection PubMed
description Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical differences and genes associated with sex reversal.
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spelling pubmed-81364472021-05-21 A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal Cordes Selby, Susan Iwata‐Otsubo, Aiko Delk, Paula Nebesio, Todd D. Gohil, Anisha Matlock, Peggy Torres‐Martinez, Wilfredo Vance, Gail H. Clin Case Rep Case Reports Two siblings with the same male unbalanced karyotype demonstrate sex reversal. The older sib appeared phenotypically female and the younger sib demonstrated a male gender. The female had gonadal dysgenesis with bilateral ovatestes. The male had bilateral testes. The report discusses the phenotypical differences and genes associated with sex reversal. John Wiley and Sons Inc. 2021-05-06 /pmc/articles/PMC8136447/ /pubmed/34026173 http://dx.doi.org/10.1002/ccr3.4141 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Cordes Selby, Susan
Iwata‐Otsubo, Aiko
Delk, Paula
Nebesio, Todd D.
Gohil, Anisha
Matlock, Peggy
Torres‐Martinez, Wilfredo
Vance, Gail H.
A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title_full A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title_fullStr A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title_full_unstemmed A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title_short A brother and sister with the same karyotype: Case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
title_sort brother and sister with the same karyotype: case report of two siblings with partial 3p duplication and partial 9p deletion and sex reversal
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136447/
https://www.ncbi.nlm.nih.gov/pubmed/34026173
http://dx.doi.org/10.1002/ccr3.4141
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