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Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis

Schamberg disease is a type of pigmented purpuric dermatosis (PPD), which is a benign cutaneous capillaritis characterized by macules and patches most commonly found on the lower extremities. Rutoside and ascorbic acid have been shown in previous cases to be efficacious in the treatment of PPD lesio...

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Autores principales: Morquette, Alexandra J, Lee, Jason B, Grossman, Shoshana K, Hsu, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136452/
https://www.ncbi.nlm.nih.gov/pubmed/34036010
http://dx.doi.org/10.7759/cureus.14592
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author Morquette, Alexandra J
Lee, Jason B
Grossman, Shoshana K
Hsu, Sylvia
author_facet Morquette, Alexandra J
Lee, Jason B
Grossman, Shoshana K
Hsu, Sylvia
author_sort Morquette, Alexandra J
collection PubMed
description Schamberg disease is a type of pigmented purpuric dermatosis (PPD), which is a benign cutaneous capillaritis characterized by macules and patches most commonly found on the lower extremities. Rutoside and ascorbic acid have been shown in previous cases to be efficacious in the treatment of PPD lesions due to their free radical scavenging effect on capillaries. We present the case of a 19-year-old woman with Schamberg disease who achieved complete clearance of lesions within four months of daily rutoside and ascorbic acid treatment. The goal of this case report is to further demonstrate the effectiveness of this treatment and to call for investigation of its use as a standard of care in PPD.
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spelling pubmed-81364522021-05-24 Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis Morquette, Alexandra J Lee, Jason B Grossman, Shoshana K Hsu, Sylvia Cureus Dermatology Schamberg disease is a type of pigmented purpuric dermatosis (PPD), which is a benign cutaneous capillaritis characterized by macules and patches most commonly found on the lower extremities. Rutoside and ascorbic acid have been shown in previous cases to be efficacious in the treatment of PPD lesions due to their free radical scavenging effect on capillaries. We present the case of a 19-year-old woman with Schamberg disease who achieved complete clearance of lesions within four months of daily rutoside and ascorbic acid treatment. The goal of this case report is to further demonstrate the effectiveness of this treatment and to call for investigation of its use as a standard of care in PPD. Cureus 2021-04-20 /pmc/articles/PMC8136452/ /pubmed/34036010 http://dx.doi.org/10.7759/cureus.14592 Text en Copyright © 2021, Morquette et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Morquette, Alexandra J
Lee, Jason B
Grossman, Shoshana K
Hsu, Sylvia
Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title_full Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title_fullStr Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title_full_unstemmed Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title_short Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis
title_sort rutoside and ascorbic acid in the treatment of schamberg pigmented purpuric dermatosis
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136452/
https://www.ncbi.nlm.nih.gov/pubmed/34036010
http://dx.doi.org/10.7759/cureus.14592
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