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Were Ancestral Proteins Less Specific?
Some have hypothesized that ancestral proteins were, on average, less specific than their descendants. If true, this would provide a universal axis along which to organize protein evolution and suggests that reconstructed ancestral proteins may be uniquely powerful tools for protein engineering. Anc...
Autores principales: | Wheeler, Lucas C, Harms, Michael J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136485/ https://www.ncbi.nlm.nih.gov/pubmed/33528559 http://dx.doi.org/10.1093/molbev/msab019 |
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