Cargando…

Constitutive activation of CTNNB1 results in a loss of spermatogonial stem cell activity in mice

Spermatogenesis requires that a careful balance be maintained between the self-renewal of spermatogonial stem cells (SSCs) and their commitment to the developmental pathway through which they will differentiate into spermatozoa. Recently, a series of studies employing various in vivo and in vitro mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boyer, Alexandre, Zhang, Xiangfan, Levasseur, Adrien, Abou Nader, Nour, St-Jean, Guillaume, Nagano, Makoto C., Boerboom, Derek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136708/ https://www.ncbi.nlm.nih.gov/pubmed/34015032 http://dx.doi.org/10.1371/journal.pone.0251911

Ejemplares similares

CTNNB1 Signaling in Sertoli Cells Downregulates Spermatogonial Stem Cell Activity via WNT4
por: Boyer, Alexandre, et al.
Publicado: (2012)

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate
por: Abou Nader, Nour, et al.
Publicado: (2022)

Effect of Inactivation of Mst1 and Mst2 in the Mouse Adrenal Cortex
por: Abou Nader, Nour, et al.
Publicado: (2022)

The Application of Biomarkers of Spermatogonial Stem Cells for Restoring Male Fertility
por: Ebata, Kevin T., et al.
Publicado: (2008)

Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis
por: Richards, JoAnne S., et al.
Publicado: (2011)

Indirect Effects of Wnt3a/β-Catenin Signalling Support Mouse Spermatogonial Stem Cells In Vitro
por: Yeh, Jonathan R., et al.
Publicado: (2012)

Dissecting the spermatogonial stem cell niche using spatial transcriptomics
por: Rajachandran, Shreya, et al.
Publicado: (2023)

mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice
por: Boyer, Alexandre, et al.
Publicado: (2016)

Activating mutations in CTNNB1 in aldosterone producing adenomas
por: Åkerström, Tobias, et al.
Publicado: (2016)

Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
por: Nóbrega, Rafael Henrique, et al.
Publicado: (2010)

Screening of Potential Plasticizer Alternatives for Their Toxic Effects on Male Germline Stem Cells
por: Zhang, Xiangfan, et al.
Publicado: (2022)

Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse
por: Wu, Chongyang, et al.
Publicado: (2016)

Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex
por: Abou Nader, Nour, et al.
Publicado: (2022)

Loss of CDYL Results in Suppression of CTNNB1 and Decreased Endometrial Receptivity
por: Zhou, Xiaowei, et al.
Publicado: (2020)

Dimethyloxaloylglycine promotes spermatogenesis activity of spermatogonial stem cells in Bama minipigs
por: Cao, Yaqi, et al.
Publicado: (2022)

CTNNB1 in neurodevelopmental disorders
por: Zhuang, Wenting, et al.
Publicado: (2023)

Plasticity of spermatogonial stem cells
por: Cooke, Paul S, et al.
Publicado: (2015)

Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice
por: Diao, Fan, et al.
Publicado: (2016)

The Role of CTNNB1 in Endometrial Cancer
por: Ledinek, Živa, et al.
Publicado: (2022)

Spermatogonial stem cell regulation and spermatogenesis
por: Phillips, Bart T., et al.
Publicado: (2010)

Spermatogonial stem cells: progress and prospects
por: Komeya, Mitsuru, et al.
Publicado: (2015)

Characterization of Spermatogonial Stem Cells Lacking Intercellular Bridges and Genetic Replacement of a Mutation in Spermatogonial Stem Cells
por: Iwamori, Naoki, et al.
Publicado: (2012)

Endocrine Regulation of Spermatogonial Stem Cells in the Seminiferous Epithelium of Adult Mice
por: Caires, Kyle C., et al.
Publicado: (2012)

Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats
por: TIPTANAVATTANA, Narong, et al.
Publicado: (2015)

Genetic and clinical characteristics of 24 mainland Chinese patients with CTNNB1 loss‐of‐function variants
por: Yan, Dan, et al.
Publicado: (2022)

CTNNB1 Mutation in Aldosterone Producing Adenoma
por: Wang, Jian-Jhong, et al.
Publicado: (2017)

CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma
por: Apps, J. R., et al.
Publicado: (2020)

Recurrent CTNNB1 mutations in craniofacial osteomas
por: Baumhoer, Daniel, et al.
Publicado: (2021)

Ovarian insufficiency and CTNNB1 mutations drive malignant transformation of endometrial hyperplasia with altered PTEN/PI3K activities
por: Terakawa, Jumpei, et al.
Publicado: (2019)

Isolation and characterization of human spermatogonial stem cells
por: Liu, Shixue, et al.
Publicado: (2011)

Spermatogonial stem cells, infertility and testicular cancer
por: Singh, Shree Ram, et al.
Publicado: (2011)

Phenotypic Plasticity of Mouse Spermatogonial Stem Cells
por: Morimoto, Hiroko, et al.
Publicado: (2009)

Spermatogonial Stem Cell Markers and Niche in Equids
por: Costa, Guilherme M. J., et al.
Publicado: (2012)

Differentiation of Bovine Spermatogonial Stem Cells into Osteoblasts
por: Qasemi-Panahi, Babak, et al.
Publicado: (2011)

Manipulation of spermatogonial stem cells in livestock species
por: Savvulidi, Filipp, et al.
Publicado: (2019)

Spermatogonial Stem Cell Transplantation in Large Animals
por: Zhao, Xin, et al.
Publicado: (2021)

Gene expression and pathway analysis of CTNNB1 in cancer and stem cells
por: Tanabe, Shihori, et al.
Publicado: (2016)

LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathway
por: ZHUANG, YAN, et al.
Publicado: (2023)

Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression
por: Liu, Tao, et al.
Publicado: (2023)

Eif2s3y Promotes the Proliferation of Spermatogonial Stem Cells by Activating ERK Signaling
por: Zhang, Mengfei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ske54qt55f3nh8c9ctk94nmljq