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Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City
During the first phase of the COVID-19 epidemic, New York City rapidly became the epicenter of the pandemic in the United States. While molecular phylogenetic analyses have previously highlighted multiple introductions and a period of cryptic community transmission within New York City, little is kn...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136714/ https://www.ncbi.nlm.nih.gov/pubmed/34015049 http://dx.doi.org/10.1371/journal.ppat.1009571 |
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author | Dellicour, Simon Hong, Samuel L. Vrancken, Bram Chaillon, Antoine Gill, Mandev S. Maurano, Matthew T. Ramaswami, Sitharam Zappile, Paul Marier, Christian Harkins, Gordon W. Baele, Guy Duerr, Ralf Heguy, Adriana |
author_facet | Dellicour, Simon Hong, Samuel L. Vrancken, Bram Chaillon, Antoine Gill, Mandev S. Maurano, Matthew T. Ramaswami, Sitharam Zappile, Paul Marier, Christian Harkins, Gordon W. Baele, Guy Duerr, Ralf Heguy, Adriana |
author_sort | Dellicour, Simon |
collection | PubMed |
description | During the first phase of the COVID-19 epidemic, New York City rapidly became the epicenter of the pandemic in the United States. While molecular phylogenetic analyses have previously highlighted multiple introductions and a period of cryptic community transmission within New York City, little is known about the circulation of SARS-CoV-2 within and among its boroughs. We here perform phylogeographic investigations to gain insights into the circulation of viral lineages during the first months of the New York City outbreak. Our analyses describe the dispersal dynamics of viral lineages at the state and city levels, illustrating that peripheral samples likely correspond to distinct dispersal events originating from the main metropolitan city areas. In line with the high prevalence recorded in this area, our results highlight the relatively important role of the borough of Queens as a transmission hub associated with higher local circulation and dispersal of viral lineages toward the surrounding boroughs. |
format | Online Article Text |
id | pubmed-8136714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-81367142021-06-02 Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City Dellicour, Simon Hong, Samuel L. Vrancken, Bram Chaillon, Antoine Gill, Mandev S. Maurano, Matthew T. Ramaswami, Sitharam Zappile, Paul Marier, Christian Harkins, Gordon W. Baele, Guy Duerr, Ralf Heguy, Adriana PLoS Pathog Research Article During the first phase of the COVID-19 epidemic, New York City rapidly became the epicenter of the pandemic in the United States. While molecular phylogenetic analyses have previously highlighted multiple introductions and a period of cryptic community transmission within New York City, little is known about the circulation of SARS-CoV-2 within and among its boroughs. We here perform phylogeographic investigations to gain insights into the circulation of viral lineages during the first months of the New York City outbreak. Our analyses describe the dispersal dynamics of viral lineages at the state and city levels, illustrating that peripheral samples likely correspond to distinct dispersal events originating from the main metropolitan city areas. In line with the high prevalence recorded in this area, our results highlight the relatively important role of the borough of Queens as a transmission hub associated with higher local circulation and dispersal of viral lineages toward the surrounding boroughs. Public Library of Science 2021-05-20 /pmc/articles/PMC8136714/ /pubmed/34015049 http://dx.doi.org/10.1371/journal.ppat.1009571 Text en © 2021 Dellicour et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Dellicour, Simon Hong, Samuel L. Vrancken, Bram Chaillon, Antoine Gill, Mandev S. Maurano, Matthew T. Ramaswami, Sitharam Zappile, Paul Marier, Christian Harkins, Gordon W. Baele, Guy Duerr, Ralf Heguy, Adriana Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title | Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title_full | Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title_fullStr | Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title_full_unstemmed | Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title_short | Dispersal dynamics of SARS-CoV-2 lineages during the first epidemic wave in New York City |
title_sort | dispersal dynamics of sars-cov-2 lineages during the first epidemic wave in new york city |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136714/ https://www.ncbi.nlm.nih.gov/pubmed/34015049 http://dx.doi.org/10.1371/journal.ppat.1009571 |
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