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Implication of repeat insertion domains in the trans-activity of the long non-coding RNA ANRIL

Long non-coding RNAs have emerged as critical regulators of cell homeostasis by modulating gene expression at chromatin level for instance. Here, we report that the lncRNA ANRIL, associated with several pathologies, binds to thousands of loci dispersed throughout the mammalian genome sharing a 21-bp...

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Detalles Bibliográficos
Autores principales: Alfeghaly, Charbel, Sanchez, Aymeric, Rouget, Raphael, Thuillier, Quentin, Igel-Bourguignon, Valérie, Marchand, Virginie, Branlant, Christiane, Motorin, Yuri, Behm-Ansmant, Isabelle, Maenner, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136789/
https://www.ncbi.nlm.nih.gov/pubmed/33872355
http://dx.doi.org/10.1093/nar/gkab245