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Asymmetry in histone rotation in forced unwrapping and force quench rewrapping in a nucleosome
Single molecule pulling experiments have shown that DNA in the nucleosomes unwraps in two stages from the histone protein core (HPC). The first stage, attributed to the rupture of the outer DNA turn, occurs between 3 and 5 pNs, and is reversible. The inner DNA turn ruptures irreversibly at forces be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136794/ https://www.ncbi.nlm.nih.gov/pubmed/33877361 http://dx.doi.org/10.1093/nar/gkab263 |