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A model of dopamine and serotonin-kynurenine metabolism in cortisolemia: Implications for depression

A major factor contributing to the etiology of depression is a neurochemical imbalance of the dopaminergic and serotonergic systems, which is caused by persistently high levels of circulating stress hormones. Here, a computational model is proposed to investigate the interplay between dopaminergic a...

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Detalles Bibliográficos
Autores principales: Dalvi-Garcia, Felipe, Fonseca, Luis L., Vasconcelos, Ana Tereza R., Hedin-Pereira, Cecilia, Voit, Eberhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136856/
https://www.ncbi.nlm.nih.gov/pubmed/33970902
http://dx.doi.org/10.1371/journal.pcbi.1008956