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A model of dopamine and serotonin-kynurenine metabolism in cortisolemia: Implications for depression
A major factor contributing to the etiology of depression is a neurochemical imbalance of the dopaminergic and serotonergic systems, which is caused by persistently high levels of circulating stress hormones. Here, a computational model is proposed to investigate the interplay between dopaminergic a...
Autores principales: | Dalvi-Garcia, Felipe, Fonseca, Luis L., Vasconcelos, Ana Tereza R., Hedin-Pereira, Cecilia, Voit, Eberhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136856/ https://www.ncbi.nlm.nih.gov/pubmed/33970902 http://dx.doi.org/10.1371/journal.pcbi.1008956 |
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