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Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children: A protocol for systematic review and meta-analysis

BACKGROUND: : The gene mutation of coding sodium channel is one of the most important mechanisms in the pathogenesis of epilepsy. There exists a large inter-individual variation in the efficacy of valproic acid (VPA) against epilepsy. What are the genetic polymorphism influences of sodium channels o...

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Detalles Bibliográficos
Autores principales: Wen, Zhuangfei, Chen, Jiang, Zhu, Bin, Lu, Yan, Chen, Lijiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136989/
https://www.ncbi.nlm.nih.gov/pubmed/34011048
http://dx.doi.org/10.1097/MD.0000000000025831

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