A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP

Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the diagnosis and treatment of the underlying malignancy. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Minsu, Lee, Ji Yun, Kim, Soo-Chan, Na, Jung-Im
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137331/
https://www.ncbi.nlm.nih.gov/pubmed/34079187
http://dx.doi.org/10.5021/ad.2021.33.3.271
_version_ 1783695601176674304
author Kim, Minsu
Lee, Ji Yun
Kim, Soo-Chan
Na, Jung-Im
author_facet Kim, Minsu
Lee, Ji Yun
Kim, Soo-Chan
Na, Jung-Im
author_sort Kim, Minsu
collection PubMed
description Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the diagnosis and treatment of the underlying malignancy. However, involvement of the respiratory system is typically unresponsive to treatment. Herein, we report the case of a 44-year-old female diagnosed with paraneoplastic pemphigus with underlying follicular lymphoma treated with a chemotherapy regimen including rituximab. Her skin lesions and underlying lymphoma responded to treatment, but bronchiolitis obliterans continued to progress and resulted in fatal respiratory failure.
format Online
Article
Text
id pubmed-8137331
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Korean Dermatological Association; The Korean Society for Investigative Dermatology
record_format MEDLINE/PubMed
spelling pubmed-81373312021-06-01 A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP Kim, Minsu Lee, Ji Yun Kim, Soo-Chan Na, Jung-Im Ann Dermatol Case Report Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the diagnosis and treatment of the underlying malignancy. However, involvement of the respiratory system is typically unresponsive to treatment. Herein, we report the case of a 44-year-old female diagnosed with paraneoplastic pemphigus with underlying follicular lymphoma treated with a chemotherapy regimen including rituximab. Her skin lesions and underlying lymphoma responded to treatment, but bronchiolitis obliterans continued to progress and resulted in fatal respiratory failure. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021-06 2021-05-04 /pmc/articles/PMC8137331/ /pubmed/34079187 http://dx.doi.org/10.5021/ad.2021.33.3.271 Text en Copyright © 2021 The Korean Dermatological Association and The Korean Society for Investigative Dermatology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Minsu
Lee, Ji Yun
Kim, Soo-Chan
Na, Jung-Im
A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title_full A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title_fullStr A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title_full_unstemmed A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title_short A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP
title_sort case of paraneoplastic pemphigus as a preceding manifestation of underlying follicular lymphoma treated with r-chop
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137331/
https://www.ncbi.nlm.nih.gov/pubmed/34079187
http://dx.doi.org/10.5021/ad.2021.33.3.271
work_keys_str_mv AT kimminsu acaseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT leejiyun acaseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT kimsoochan acaseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT najungim acaseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT kimminsu caseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT leejiyun caseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT kimsoochan caseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop
AT najungim caseofparaneoplasticpemphigusasaprecedingmanifestationofunderlyingfollicularlymphomatreatedwithrchop

Ejemplares similares