Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens

Three assays for SARS-CoV-2 antigen detection in nasopharyngeal swabs (Lumipulse® G SARS-CoV-2 Ag [LPG], STANDARD(TM) F COVID-19 Ag FIA [STF] and AFIAS COVID-19 Ag [AFC] were evaluated. Compared to RT-PCR, LPG, AFC and STF showed a variable sensitivity (87.9%, 37.5%, and 35.7%, respectively) and an...

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Autores principales: Baccani, Ilaria, Morecchiato, Fabio, Chilleri, Chiara, Cervini, Chiara, Gori, Emanuele, Matarrese, Daniela, Bassetti, Andrea, Bonizzoli, Manuela, Mencarini, Jessica, Antonelli, Alberto, Rossolini, Gian Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137375/
https://www.ncbi.nlm.nih.gov/pubmed/34174523
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115434
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author Baccani, Ilaria
Morecchiato, Fabio
Chilleri, Chiara
Cervini, Chiara
Gori, Emanuele
Matarrese, Daniela
Bassetti, Andrea
Bonizzoli, Manuela
Mencarini, Jessica
Antonelli, Alberto
Rossolini, Gian Maria
author_facet Baccani, Ilaria
Morecchiato, Fabio
Chilleri, Chiara
Cervini, Chiara
Gori, Emanuele
Matarrese, Daniela
Bassetti, Andrea
Bonizzoli, Manuela
Mencarini, Jessica
Antonelli, Alberto
Rossolini, Gian Maria
author_sort Baccani, Ilaria
collection PubMed
description Three assays for SARS-CoV-2 antigen detection in nasopharyngeal swabs (Lumipulse® G SARS-CoV-2 Ag [LPG], STANDARD(TM) F COVID-19 Ag FIA [STF] and AFIAS COVID-19 Ag [AFC] were evaluated. Compared to RT-PCR, LPG, AFC and STF showed a variable sensitivity (87.9%, 37.5%, and 35.7%, respectively) and an overall high specificity (> 95%).
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spelling pubmed-81373752021-05-21 Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens Baccani, Ilaria Morecchiato, Fabio Chilleri, Chiara Cervini, Chiara Gori, Emanuele Matarrese, Daniela Bassetti, Andrea Bonizzoli, Manuela Mencarini, Jessica Antonelli, Alberto Rossolini, Gian Maria Diagn Microbiol Infect Dis Article Three assays for SARS-CoV-2 antigen detection in nasopharyngeal swabs (Lumipulse® G SARS-CoV-2 Ag [LPG], STANDARD(TM) F COVID-19 Ag FIA [STF] and AFIAS COVID-19 Ag [AFC] were evaluated. Compared to RT-PCR, LPG, AFC and STF showed a variable sensitivity (87.9%, 37.5%, and 35.7%, respectively) and an overall high specificity (> 95%). Elsevier Inc. 2021-10 2021-05-21 /pmc/articles/PMC8137375/ /pubmed/34174523 http://dx.doi.org/10.1016/j.diagmicrobio.2021.115434 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Baccani, Ilaria
Morecchiato, Fabio
Chilleri, Chiara
Cervini, Chiara
Gori, Emanuele
Matarrese, Daniela
Bassetti, Andrea
Bonizzoli, Manuela
Mencarini, Jessica
Antonelli, Alberto
Rossolini, Gian Maria
Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title_full Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title_fullStr Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title_full_unstemmed Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title_short Evaluation of Three Immunoassays for the Rapid Detection of SARS-CoV-2 antigens
title_sort evaluation of three immunoassays for the rapid detection of sars-cov-2 antigens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137375/
https://www.ncbi.nlm.nih.gov/pubmed/34174523
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115434
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