Cargando…

Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release

Bone marrow-derived human mesenchymal stem cells (hMSCs) are recruited to damaged or inflamed tissues where they contribute to tissue repair. This multi-step process involves chemokine-directed invasion of hMSCs and on-site release of factors that influence target cells or tumor tissues. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Egea, Virginia, Kessenbrock, Kai, Lawson, Devon, Bartelt, Alexander, Weber, Christian, Ries, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137693/
https://www.ncbi.nlm.nih.gov/pubmed/34016957
http://dx.doi.org/10.1038/s41419-021-03789-3