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Modified adeno‐associated virus targets the bacterial enzyme chondroitinase ABC to select mouse neuronal populations in vivo using the Cre‐LoxP system

Current methods of experimentally degrading the specialized extracellular matrix (ECM), perineuronal nets (PNNs) have several limitations. Genetic knockout of ECM components typically has only partial effects on PNNs, and knockout of the major ECM component aggrecan is lethal in mice. Direct injecti...

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Detalles Bibliográficos
Autores principales:	Carstens, Kelly E., Gloss, Bernd R., Alexander, Georgia M., Dudek, Serena M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Special Issue Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137719/ https://www.ncbi.nlm.nih.gov/pubmed/33220084 http://dx.doi.org/10.1111/ejn.15050

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