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Targeting DNA Damage Repair for Immune Checkpoint Inhibition: Mechanisms and Potential Clinical Applications

DNA damage repair (DDR) pathways play an essential role in maintaining genomic integrity. DDR dysfunction leads to accumulated DNA damage, predisposition to cancer, and high sensitivity to chemotherapy and radiotherapy. Recent studies have demonstrated that DDR status is associated with response to...

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Detalles Bibliográficos
Autores principales:	Sun, Wei, Zhang, Qing, Wang, Runkun, Li, Yang, Sun, Yue, Yang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137908/ https://www.ncbi.nlm.nih.gov/pubmed/34026622 http://dx.doi.org/10.3389/fonc.2021.648687

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