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Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety

Background: There is a bidirectional relationship between blood pressure variability (BPV) and anxiety, but few studies have examined the gender- and age-specific effects of visit-to-visit BPV on incident anxiety. We examined the predictive value of BPV for the incidence of anxiety in a family clini...

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Autores principales: Zhou, Jiandong, Lee, Sharen, Wong, Wing Tak, Leung, Keith Sai Kit, Nam, Ronald Hang Kin, Leung, Prudence Shun Hay, Chau, Yau-Lam Alex, Liu, Tong, Chang, Carlin, Cheung, Bernard Man Yung, Tse, Gary, Zhang, Qingpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137912/
https://www.ncbi.nlm.nih.gov/pubmed/34026870
http://dx.doi.org/10.3389/fcvm.2021.650852
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author Zhou, Jiandong
Lee, Sharen
Wong, Wing Tak
Leung, Keith Sai Kit
Nam, Ronald Hang Kin
Leung, Prudence Shun Hay
Chau, Yau-Lam Alex
Liu, Tong
Chang, Carlin
Cheung, Bernard Man Yung
Tse, Gary
Zhang, Qingpeng
author_facet Zhou, Jiandong
Lee, Sharen
Wong, Wing Tak
Leung, Keith Sai Kit
Nam, Ronald Hang Kin
Leung, Prudence Shun Hay
Chau, Yau-Lam Alex
Liu, Tong
Chang, Carlin
Cheung, Bernard Man Yung
Tse, Gary
Zhang, Qingpeng
author_sort Zhou, Jiandong
collection PubMed
description Background: There is a bidirectional relationship between blood pressure variability (BPV) and anxiety, but few studies have examined the gender- and age-specific effects of visit-to-visit BPV on incident anxiety. We examined the predictive value of BPV for the incidence of anxiety in a family clinic cohort. Methods: Consecutive patients with a first attendance to family medicine clinics in Hong Kong between January 1, 2000, and December 31, 2002, with at least three blood pressure measurements available thereafter were included. The primary endpoint was incident anxiety as identified by ICD-9 coding. Results: This study included 48,023 (50% males) patients with a median follow-up of 224 [interquartile range (IQR): 217–229] months. Females were more likely to develop incident anxiety compared to males (incidence rate: 7 vs. 2%), as were patients of older age. Significant univariate predictors were female gender, older age, preexisting cardiovascular diseases, respiratory diseases, diabetes mellitus, hypertension, and gastrointestinal diseases, various laboratory examinations, and the number of blood pressure measurements. Higher baseline, maximum, minimum, standard deviation (SD), coefficient of variation (CV), and variability score of diastolic blood pressure significantly predicted incident anxiety, as did all systolic blood pressure measures [baseline, latest, maximum, minimum, mean, median, variance, SD, root mean square (RMS), CV, and variability score]. Conclusions: The relationships between longer-term visit-to-visit BPV and incident anxiety were identified. Female and older patients with higher blood pressure and higher BPV were at the highest risks of incident anxiety.
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spelling pubmed-81379122021-05-22 Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety Zhou, Jiandong Lee, Sharen Wong, Wing Tak Leung, Keith Sai Kit Nam, Ronald Hang Kin Leung, Prudence Shun Hay Chau, Yau-Lam Alex Liu, Tong Chang, Carlin Cheung, Bernard Man Yung Tse, Gary Zhang, Qingpeng Front Cardiovasc Med Cardiovascular Medicine Background: There is a bidirectional relationship between blood pressure variability (BPV) and anxiety, but few studies have examined the gender- and age-specific effects of visit-to-visit BPV on incident anxiety. We examined the predictive value of BPV for the incidence of anxiety in a family clinic cohort. Methods: Consecutive patients with a first attendance to family medicine clinics in Hong Kong between January 1, 2000, and December 31, 2002, with at least three blood pressure measurements available thereafter were included. The primary endpoint was incident anxiety as identified by ICD-9 coding. Results: This study included 48,023 (50% males) patients with a median follow-up of 224 [interquartile range (IQR): 217–229] months. Females were more likely to develop incident anxiety compared to males (incidence rate: 7 vs. 2%), as were patients of older age. Significant univariate predictors were female gender, older age, preexisting cardiovascular diseases, respiratory diseases, diabetes mellitus, hypertension, and gastrointestinal diseases, various laboratory examinations, and the number of blood pressure measurements. Higher baseline, maximum, minimum, standard deviation (SD), coefficient of variation (CV), and variability score of diastolic blood pressure significantly predicted incident anxiety, as did all systolic blood pressure measures [baseline, latest, maximum, minimum, mean, median, variance, SD, root mean square (RMS), CV, and variability score]. Conclusions: The relationships between longer-term visit-to-visit BPV and incident anxiety were identified. Female and older patients with higher blood pressure and higher BPV were at the highest risks of incident anxiety. Frontiers Media S.A. 2021-05-07 /pmc/articles/PMC8137912/ /pubmed/34026870 http://dx.doi.org/10.3389/fcvm.2021.650852 Text en Copyright © 2021 Zhou, Lee, Wong, Leung, Nam, Leung, Chau, Liu, Chang, Cheung, Tse and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zhou, Jiandong
Lee, Sharen
Wong, Wing Tak
Leung, Keith Sai Kit
Nam, Ronald Hang Kin
Leung, Prudence Shun Hay
Chau, Yau-Lam Alex
Liu, Tong
Chang, Carlin
Cheung, Bernard Man Yung
Tse, Gary
Zhang, Qingpeng
Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title_full Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title_fullStr Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title_full_unstemmed Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title_short Gender- and Age-Specific Associations of Visit-to-Visit Blood Pressure Variability With Anxiety
title_sort gender- and age-specific associations of visit-to-visit blood pressure variability with anxiety
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137912/
https://www.ncbi.nlm.nih.gov/pubmed/34026870
http://dx.doi.org/10.3389/fcvm.2021.650852
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