Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation

The eukaryotic signal recognition particle (SRP) contains an Alu domain, which docks into the factor binding site of translating ribosomes and confers translation retardation. The canonical Alu domain consists of the SRP9/14 protein heterodimer and a tRNA-like folded Alu RNA that adopts a strictly ‘...

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Detalles Bibliográficos
Autores principales: Soni, Komal, Kempf, Georg, Manalastas-Cantos, Karen, Hendricks, Astrid, Flemming, Dirk, Guizetti, Julien, Simon, Bernd, Frischknecht, Friedrich, Svergun, Dmitri I., Wild, Klemens, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137916/
https://www.ncbi.nlm.nih.gov/pubmed/34017052
http://dx.doi.org/10.1038/s42003-021-02132-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137916/
https://www.ncbi.nlm.nih.gov/pubmed/34017052
http://dx.doi.org/10.1038/s42003-021-02132-y

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