Structural insights on ligand recognition at the human leukotriene B4 receptor 1

The leukotriene B4 receptor 1 (BLT1) regulates the recruitment and chemotaxis of different cell types and plays a role in the pathophysiology of infectious, allergic, metabolic, and tumorigenic human diseases. Here we present a crystal structure of human BLT1 (hBLT1) in complex with a selective anta...

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Detalles Bibliográficos
Autores principales: Michaelian, Nairie, Sadybekov, Anastasiia, Besserer-Offroy, Élie, Han, Gye Won, Krishnamurthy, Harini, Zamlynny, Beata A., Fradera, Xavier, Siliphaivanh, Phieng, Presland, Jeremy, Spencer, Kerrie B., Soisson, Stephen M., Popov, Petr, Sarret, Philippe, Katritch, Vsevolod, Cherezov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137929/
https://www.ncbi.nlm.nih.gov/pubmed/34016973
http://dx.doi.org/10.1038/s41467-021-23149-1

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