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Total Flavonoids of Glycyrrhiza uralensis Alleviates Irinotecan-Induced Colitis via Modification of Gut Microbiota and Fecal Metabolism

Irinotecan (CPT-11)-induced gastrointestinal toxicity strongly limits its anticancer efficacy. Glycyrrhiza uralensis Fisch., especially flavonoids, has strong anti-inflammatory and immunomodulatory activities. Herein, we investigate the protective effect of the total flavonoids of G. uralensis (TFGU...

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Detalles Bibliográficos
Autores principales:	Yue, Shi-Jun, Qin, Yi-Feng, Kang, An, Tao, Hui-Juan, Zhou, Gui-Sheng, Chen, Yan-Yan, Jiang, Jian-Qin, Tang, Yu-Ping, Duan, Jin-Ao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138048/ https://www.ncbi.nlm.nih.gov/pubmed/34025639 http://dx.doi.org/10.3389/fimmu.2021.628358

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