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Efficacy and Resistance of Afatinib in Chinese Non-Small Cell Lung Cancer Patients With HER2 Alterations: A Multicenter Retrospective Study

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with HER2 mutations and amplification may benefit from HER2-targeted therapy, including afatinib. However, the data regarding the clinical activity of afatinib in Chinese patients with NSCLC harboring HER2 alterations are limited. PATIENTS AND...

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Detalles Bibliográficos
Autores principales: Song, Zhengbo, Lv, Dongqing, Chen, Shiqing, Huang, Jianhui, Wang, Liping, Xu, Shuguang, Chen, Huafei, Wang, Guoqiang, Lin, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138059/
https://www.ncbi.nlm.nih.gov/pubmed/34026634
http://dx.doi.org/10.3389/fonc.2021.657283