Pyruvate Kinase M2 Contributes to TLR-Mediated Inflammation and Autoimmunity by Promoting Pyk2 Activation

Toll-like receptors (TLRs) play critical roles in regulating the abnormal activation of the immune cells resulting in the pathogenesis of inflammation and autoimmune diseases. Pyruvate kinase M2 (PKM2), which governs the last step of glycolysis, is involved in multiple cellular processes and patholo...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Yang, Yonghong, Jing, Lina, Zhai, Weiwei, Zhang, Hui, Ma, Qun, Li, Chunxia, Yan, Fenglian, Cheng, Dalei, Zhang, Junfeng, Ning, Zhaochen, Shi, Hui, Wang, Changying, Zhao, Mingsheng, Dai, Jun, Li, Zhihua, Ming, Jiankuo, Yu, Meimei, Wang, Haiyan, Cheng, Hongyan, Xiong, Huabao, Dong, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138060/
https://www.ncbi.nlm.nih.gov/pubmed/34025679
http://dx.doi.org/10.3389/fimmu.2021.680068

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