PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Proteolysis targeting chimeric (PROTAC) technology is an effective endogenous protein degradation tool developed in recent years that can ubiquitinate the target proteins through the ubiquitin-proteasome system (UPS) to achieve an effect on tumor growth. A number of literature studies on PROTAC tech...

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Detalles Bibliográficos
Autores principales: Qi, Si-Min, Dong, Jinyun, Xu, Zhi-Yuan, Cheng, Xiang-Dong, Zhang, Wei-Dong, Qin, Jiang-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138175/
https://www.ncbi.nlm.nih.gov/pubmed/34025443
http://dx.doi.org/10.3389/fphar.2021.692574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138175/
https://www.ncbi.nlm.nih.gov/pubmed/34025443
http://dx.doi.org/10.3389/fphar.2021.692574

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