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Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient

We present a pediatric case to highlight the clinical appearance and management of choroidal neovascularization in the setting of active toxoplasma retinochoroiditis (TRC). A 17-year-old female presented with 2 days of blurry vision in her left eye. Retinal examination demonstrated a pigmented chori...

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Autores principales: Khandwala, Nikhila S., Hyde, Robert A., Besirli, Cagri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138240/
https://www.ncbi.nlm.nih.gov/pubmed/34054467
http://dx.doi.org/10.1159/000512286
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author Khandwala, Nikhila S.
Hyde, Robert A.
Besirli, Cagri G.
author_facet Khandwala, Nikhila S.
Hyde, Robert A.
Besirli, Cagri G.
author_sort Khandwala, Nikhila S.
collection PubMed
description We present a pediatric case to highlight the clinical appearance and management of choroidal neovascularization in the setting of active toxoplasma retinochoroiditis (TRC). A 17-year-old female presented with 2 days of blurry vision in her left eye. Retinal examination demonstrated a pigmented chorioretinal lesion with associated subretinal fluid, vessel sheathing, and adjacent intraretinal hemorrhage. She was diagnosed with active choroidal neovascularization and successful treatment with bevacizumab revealed an underlying active toxoplasmosis lesion. Choroidal neovascularization may rarely present during an acute case of TRC. Dual therapy with anti-vascular endothelial growth factor antibody and anti-parasitic agents leads to improved visual outcomes.
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spelling pubmed-81382402021-05-27 Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient Khandwala, Nikhila S. Hyde, Robert A. Besirli, Cagri G. Case Rep Ophthalmol Case Report We present a pediatric case to highlight the clinical appearance and management of choroidal neovascularization in the setting of active toxoplasma retinochoroiditis (TRC). A 17-year-old female presented with 2 days of blurry vision in her left eye. Retinal examination demonstrated a pigmented chorioretinal lesion with associated subretinal fluid, vessel sheathing, and adjacent intraretinal hemorrhage. She was diagnosed with active choroidal neovascularization and successful treatment with bevacizumab revealed an underlying active toxoplasmosis lesion. Choroidal neovascularization may rarely present during an acute case of TRC. Dual therapy with anti-vascular endothelial growth factor antibody and anti-parasitic agents leads to improved visual outcomes. S. Karger AG 2021-04-16 /pmc/articles/PMC8138240/ /pubmed/34054467 http://dx.doi.org/10.1159/000512286 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Khandwala, Nikhila S.
Hyde, Robert A.
Besirli, Cagri G.
Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title_full Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title_fullStr Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title_full_unstemmed Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title_short Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient
title_sort toxoplasma retinochoroiditis with chorioretinal neovascularization in a young patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138240/
https://www.ncbi.nlm.nih.gov/pubmed/34054467
http://dx.doi.org/10.1159/000512286
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