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Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report
Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138253/ https://www.ncbi.nlm.nih.gov/pubmed/34054465 http://dx.doi.org/10.1159/000510844 |
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author | Zhu, Ye-Tao Liu, Yang Chen, Li-Gang Song, Da-Ping |
author_facet | Zhu, Ye-Tao Liu, Yang Chen, Li-Gang Song, Da-Ping |
author_sort | Zhu, Ye-Tao |
collection | PubMed |
description | Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient's tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored. |
format | Online Article Text |
id | pubmed-8138253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-81382532021-05-27 Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report Zhu, Ye-Tao Liu, Yang Chen, Li-Gang Song, Da-Ping Case Rep Neurol Single Case − General Neurology Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient's tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored. S. Karger AG 2021-04-28 /pmc/articles/PMC8138253/ /pubmed/34054465 http://dx.doi.org/10.1159/000510844 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case − General Neurology Zhu, Ye-Tao Liu, Yang Chen, Li-Gang Song, Da-Ping Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title | Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title_full | Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title_fullStr | Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title_full_unstemmed | Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title_short | Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report |
title_sort | malignant solitary fibrous tumor of the right cerebellum: a case report |
topic | Single Case − General Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138253/ https://www.ncbi.nlm.nih.gov/pubmed/34054465 http://dx.doi.org/10.1159/000510844 |
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