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Drug Repurposing on G Protein-Coupled Receptors Using a Computational Profiling Approach
G protein-coupled receptors (GPCRs) are the largest human membrane receptor family regulating a wide range of cell signaling. For this reason, GPCRs are highly desirable drug targets, with approximately 40% of prescribed medicines targeting a member of this receptor family. The structural homology o...
Autores principales: | de Felice, Alessandra, Aureli, Simone, Limongelli, Vittorio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138314/ https://www.ncbi.nlm.nih.gov/pubmed/34026848 http://dx.doi.org/10.3389/fmolb.2021.673053 |
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