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Drug Repurposing on G Protein-Coupled Receptors Using a Computational Profiling Approach

G protein-coupled receptors (GPCRs) are the largest human membrane receptor family regulating a wide range of cell signaling. For this reason, GPCRs are highly desirable drug targets, with approximately 40% of prescribed medicines targeting a member of this receptor family. The structural homology o...

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Detalles Bibliográficos
Autores principales: de Felice, Alessandra, Aureli, Simone, Limongelli, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138314/
https://www.ncbi.nlm.nih.gov/pubmed/34026848
http://dx.doi.org/10.3389/fmolb.2021.673053

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