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Association of handgrip strength and endurance with body composition in head and neck cancer patients

INTRODUCTION: Assessment of skeletal muscle function (SMF) is of clinical relevance in the prediction of treatment outcome and to decide on optimal management of head & neck cancer (HNC) patients. Handgrip strength (HGS) & handgrip endurance (HGE) are considered as surrogate marker for whole...

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Autores principales: Kowshik, Vengadesan, Velkumary, Subramanian, Sethi, Pooja, Feula, Jothi Marie, Subhashri, Soundirarajan, Abirami, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138385/
https://www.ncbi.nlm.nih.gov/pubmed/34041097
http://dx.doi.org/10.4103/jfmpc.jfmpc_1695_20
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author Kowshik, Vengadesan
Velkumary, Subramanian
Sethi, Pooja
Feula, Jothi Marie
Subhashri, Soundirarajan
Abirami, Manikandan
author_facet Kowshik, Vengadesan
Velkumary, Subramanian
Sethi, Pooja
Feula, Jothi Marie
Subhashri, Soundirarajan
Abirami, Manikandan
author_sort Kowshik, Vengadesan
collection PubMed
description INTRODUCTION: Assessment of skeletal muscle function (SMF) is of clinical relevance in the prediction of treatment outcome and to decide on optimal management of head & neck cancer (HNC) patients. Handgrip strength (HGS) & handgrip endurance (HGE) are considered as surrogate marker for whole-body skeletal muscle function. Further, SMF depends substantially on the body composition (BC). Hence in this study, we compared BC, HGS and HGE between HNC patients and healthy controls and also analysed the association of HGS, HGE with body composition in HNC patients. METHODS: A cross-sectional study, conducted in 44 subjects in the age between 18 to 60 years. Twenty-two were histologically proven HNC patients prior to cancer-specific treatment and twenty-two age and gender-matched healthy volunteers. The parameters recorded were Height, weight, waist circumference, hip circumference, HGS, HGE and BC. Hand-held dynamometer was used to measure HGS and HGE measured using a stopwatch. BC was estimated by whole-body bioelectrical Impedance analysis method using Bodystat Quad scan 4000 device. RESULT: Comparison of data between HNC patient & healthy control was done by Student's t test. HGS, HGE, lean body mass (LBM), fat-free mass index (FFMI), Phase angle (PA), body cell mass (BCM) and body cell mass index (BCMI) were found to be reduced significantly in HNC patients when compared to healthy subjects. Further, Pearson correlation analysis revealed a significant positive correlation of HGS & HGE with LBM, FFMI, PA, BCM & BCMI, whereas body fat mass index showed a negative correlation with HGS & HGE in HNC patients. CONCLUSION: Our findings revealed, a significant reduction in HGS, HGE in patient with HNC which denotes decreased skeletal muscle function and it is linearly associated with low muscle mass, body cell mass and phase angle.
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spelling pubmed-81383852021-05-25 Association of handgrip strength and endurance with body composition in head and neck cancer patients Kowshik, Vengadesan Velkumary, Subramanian Sethi, Pooja Feula, Jothi Marie Subhashri, Soundirarajan Abirami, Manikandan J Family Med Prim Care Original Article INTRODUCTION: Assessment of skeletal muscle function (SMF) is of clinical relevance in the prediction of treatment outcome and to decide on optimal management of head & neck cancer (HNC) patients. Handgrip strength (HGS) & handgrip endurance (HGE) are considered as surrogate marker for whole-body skeletal muscle function. Further, SMF depends substantially on the body composition (BC). Hence in this study, we compared BC, HGS and HGE between HNC patients and healthy controls and also analysed the association of HGS, HGE with body composition in HNC patients. METHODS: A cross-sectional study, conducted in 44 subjects in the age between 18 to 60 years. Twenty-two were histologically proven HNC patients prior to cancer-specific treatment and twenty-two age and gender-matched healthy volunteers. The parameters recorded were Height, weight, waist circumference, hip circumference, HGS, HGE and BC. Hand-held dynamometer was used to measure HGS and HGE measured using a stopwatch. BC was estimated by whole-body bioelectrical Impedance analysis method using Bodystat Quad scan 4000 device. RESULT: Comparison of data between HNC patient & healthy control was done by Student's t test. HGS, HGE, lean body mass (LBM), fat-free mass index (FFMI), Phase angle (PA), body cell mass (BCM) and body cell mass index (BCMI) were found to be reduced significantly in HNC patients when compared to healthy subjects. Further, Pearson correlation analysis revealed a significant positive correlation of HGS & HGE with LBM, FFMI, PA, BCM & BCMI, whereas body fat mass index showed a negative correlation with HGS & HGE in HNC patients. CONCLUSION: Our findings revealed, a significant reduction in HGS, HGE in patient with HNC which denotes decreased skeletal muscle function and it is linearly associated with low muscle mass, body cell mass and phase angle. Wolters Kluwer - Medknow 2021-02 2021-02-27 /pmc/articles/PMC8138385/ /pubmed/34041097 http://dx.doi.org/10.4103/jfmpc.jfmpc_1695_20 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kowshik, Vengadesan
Velkumary, Subramanian
Sethi, Pooja
Feula, Jothi Marie
Subhashri, Soundirarajan
Abirami, Manikandan
Association of handgrip strength and endurance with body composition in head and neck cancer patients
title Association of handgrip strength and endurance with body composition in head and neck cancer patients
title_full Association of handgrip strength and endurance with body composition in head and neck cancer patients
title_fullStr Association of handgrip strength and endurance with body composition in head and neck cancer patients
title_full_unstemmed Association of handgrip strength and endurance with body composition in head and neck cancer patients
title_short Association of handgrip strength and endurance with body composition in head and neck cancer patients
title_sort association of handgrip strength and endurance with body composition in head and neck cancer patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138385/
https://www.ncbi.nlm.nih.gov/pubmed/34041097
http://dx.doi.org/10.4103/jfmpc.jfmpc_1695_20
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