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Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India

INTRODUCTION: Brucellosis is a recognised occupational threat among animal handler and raw animal product consumers. In India, there is a likelihood of missed diagnoses and under-reporting cases by physicians causing an extended debilitating illness. We steered research to conclude the seroprevalenc...

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Autores principales: Ghugey, Satish L., Setia, Maninder S., Deshmukh, Jyotsna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138393/
https://www.ncbi.nlm.nih.gov/pubmed/34041116
http://dx.doi.org/10.4103/jfmpc.jfmpc_1153_20
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author Ghugey, Satish L.
Setia, Maninder S.
Deshmukh, Jyotsna S.
author_facet Ghugey, Satish L.
Setia, Maninder S.
Deshmukh, Jyotsna S.
author_sort Ghugey, Satish L.
collection PubMed
description INTRODUCTION: Brucellosis is a recognised occupational threat among animal handler and raw animal product consumers. In India, there is a likelihood of missed diagnoses and under-reporting cases by physicians causing an extended debilitating illness. We steered research to conclude the seroprevalence and risk factors allied with Human Brucellosis (HB) among the rural population in Nagpur District, Maharashtra, India. METHODS: Closed-ended questionnaires used for a cross-sectional study to collect data for demographics and risk exposure variables. 382 subjects' serum-samples were tested by using Rose-Bengal (RBPT) and ELISA technique. An odd ratio calculated for risk factors for HB reported positive or negative. Data were analysed by using SPSS. RESULTS: The brucellosis seroprevalence in rural Nagpur was 1.83%. The mean age was 42.32 years, 78.5% were male, and 21.5% were female. Prevalence was higher among males [85.7%] than females [14.3%]. The risk for brucellosis among males (OR = 1.65, 95% CI = 0.19–13.92, P = 0.64) was more than females. Handling raw meat had more risk (OR = 3.14, 95% CI = 0.40 – 28.6, P = 0.23) than those not handling raw meat. Milking animal was protective (OR = 0.88, 95% CI = 0.80 – 0.96, P < 0.001) for brucellosis than those not milking animal. Subjects reported more likely to be a seropositive to human brucellosis those involved in assisted animal delivery (P = 0.001), drinking unpasteurised milk (P<0.001), consuming milk products made from raw milk (P<0.001) and eating raw meat (P = 0.001) CONCLUSION: Health education program is essential to generate awareness for brucellosis in the rural community to prevent animal to human disease transmission.
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spelling pubmed-81383932021-05-25 Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India Ghugey, Satish L. Setia, Maninder S. Deshmukh, Jyotsna S. J Family Med Prim Care Original Article INTRODUCTION: Brucellosis is a recognised occupational threat among animal handler and raw animal product consumers. In India, there is a likelihood of missed diagnoses and under-reporting cases by physicians causing an extended debilitating illness. We steered research to conclude the seroprevalence and risk factors allied with Human Brucellosis (HB) among the rural population in Nagpur District, Maharashtra, India. METHODS: Closed-ended questionnaires used for a cross-sectional study to collect data for demographics and risk exposure variables. 382 subjects' serum-samples were tested by using Rose-Bengal (RBPT) and ELISA technique. An odd ratio calculated for risk factors for HB reported positive or negative. Data were analysed by using SPSS. RESULTS: The brucellosis seroprevalence in rural Nagpur was 1.83%. The mean age was 42.32 years, 78.5% were male, and 21.5% were female. Prevalence was higher among males [85.7%] than females [14.3%]. The risk for brucellosis among males (OR = 1.65, 95% CI = 0.19–13.92, P = 0.64) was more than females. Handling raw meat had more risk (OR = 3.14, 95% CI = 0.40 – 28.6, P = 0.23) than those not handling raw meat. Milking animal was protective (OR = 0.88, 95% CI = 0.80 – 0.96, P < 0.001) for brucellosis than those not milking animal. Subjects reported more likely to be a seropositive to human brucellosis those involved in assisted animal delivery (P = 0.001), drinking unpasteurised milk (P<0.001), consuming milk products made from raw milk (P<0.001) and eating raw meat (P = 0.001) CONCLUSION: Health education program is essential to generate awareness for brucellosis in the rural community to prevent animal to human disease transmission. Wolters Kluwer - Medknow 2021-02 2021-02-27 /pmc/articles/PMC8138393/ /pubmed/34041116 http://dx.doi.org/10.4103/jfmpc.jfmpc_1153_20 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Ghugey, Satish L.
Setia, Maninder S.
Deshmukh, Jyotsna S.
Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title_full Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title_fullStr Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title_full_unstemmed Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title_short Human brucellosis: Seroprevalence and associated exposure factors among the rural population in Nagpur, Maharashtra, India
title_sort human brucellosis: seroprevalence and associated exposure factors among the rural population in nagpur, maharashtra, india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138393/
https://www.ncbi.nlm.nih.gov/pubmed/34041116
http://dx.doi.org/10.4103/jfmpc.jfmpc_1153_20
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