Cargando…

Neuroprotective Effects of Danshen Chuanxiongqin Injection Against Ischemic Stroke: Metabolomic Insights by UHPLC-Q-Orbitrap HRMS Analysis

The incidence of cerebral ischemic stroke characterized by high mortality is increasing every year. Danshen Chuanxiongqin Injection (DSCXQ), a traditional Chinese medicine (TCM) preparation, is often applied to treat cerebral apoplexy and its related sequelae. However, there is a lack of systematic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Peipei, Zhou, Lin, Shi, Yingying, Li, Zhuolun, Liu, Liwei, Zuo, Lihua, Zhang, Jun, Liang, Shuhong, Kang, Jian, Du, Shuzhang, Yang, Jing, Sun, Zhi, Zhang, Xiaojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138457/ https://www.ncbi.nlm.nih.gov/pubmed/34026822 http://dx.doi.org/10.3389/fmolb.2021.630291

Ejemplares similares

Antiseptic Activity of Ethnomedicinal Xuebijing Revealed by the Metabolomics Analysis Using UHPLC-Q-Orbitrap HRMS
por: Zuo, Lihua, et al.
Publicado: (2018)

Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS
por: Jiang, Xiaofang, et al.
Publicado: (2020)

UHPLC-HRMS-based metabolomic and lipidomic characterization of glioma cells in response to anlotinib
por: Shi, Yingying, et al.
Publicado: (2023)

Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS
por: Bastos, Katherine Xavier, et al.
Publicado: (2017)

In Vivo Antihypertensive Activity and UHPLC-Orbitrap-HRMS Profiling of Cuphea ignea A. DC.
por: Ismail, Walaa M., et al.
Publicado: (2022)

Analysis of Isoflavones in Pueraria by UHPLC-Q-Orbitrap HRMS and Study on α-Glucosidase Inhibitory Activity
por: Yang, Yan, et al.
Publicado: (2022)

Study on Pharmacokinetics and Metabolic Profiles of Novel Potential PLK-1 Inhibitors by UHPLC-MS/MS Combined with UHPLC-Q-Orbitrap/HRMS
por: Wang, Lin, et al.
Publicado: (2023)

Target Analysis and Retrospective Screening of Multiple Mycotoxins in Pet Food Using UHPLC-Q-Orbitrap HRMS
por: Castaldo, Luigi, et al.
Publicado: (2019)

Identification of Chemical Composition of Leaves and Flowers from Paeonia rockii by UHPLC-Q-Exactive Orbitrap HRMS
por: Li, Jinhua, et al.
Publicado: (2016)

Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS
por: Izzo, Luana, et al.
Publicado: (2020)

Simultaneously qualitative and quantitative analysis of the representative components in Kadsura heteroclita stem by UHPLC-Q-Orbitrap HRMS
por: Liu, Qian-qian, et al.
Publicado: (2021)

Systematically Exploring the Chemical Ingredients and Absorbed Constituents of Polygonum capitatum in Hyperuricemia Rat Plasma Using UHPLC-Q-Orbitrap HRMS
por: Guan, Huanyu, et al.
Publicado: (2022)

Structural Identification of Impurities in Pioglitazone Hydrochloride Preparations by 2D-UHPLC-Q-Exactive Orbitrap HRMS and Their Toxicity Prediction
por: Zhang, Dandan, et al.
Publicado: (2023)

Comprehensive multiplexed analysis of risky drugs in eggs based on magnetic zeolitic imidazolate frameworks and UHPLC Q-Orbitrap HRMS
por: Jia, Wei, et al.
Publicado: (2021)

Rapid identification of chemical components in Xuelian granule by UHPLC-Q-orbitrap-HRMS based on enzyme activity in vitro
por: Taximaimaiti, Xiatiguli, et al.
Publicado: (2023)

Non-Targeted Metabolomics Combined with Chemometrics by UHPLC–Orbitrap–HRMS and Antioxidant Activity of Atractylodes chinensis (DC.) Koidez. from Eight Origins
por: Gao, Xueyan, et al.
Publicado: (2023)

Untargeted Metabolomics Analysis Using FTIR and UHPLC-Q-Orbitrap HRMS of Two Curculigo Species and Evaluation of Their Antioxidant and α-Glucosidase Inhibitory Activities
por: Umar, Abdul Halim, et al.
Publicado: (2021)

In Vitro Bioaccessibility and Antioxidant Activity of Coffee Silverskin Polyphenolic Extract and Characterization of Bioactive Compounds Using UHPLC-Q-Orbitrap HRMS
por: Castaldo, Luigi, et al.
Publicado: (2020)

Targeted UHPLC–HRMS (Orbitrap) Polyphenolic and Capsaicinoid Profiling for the Chemometric Characterization and Classification of Paprika with Protected Designation of Origin (PDO) Attributes
por: Barbosa, Sergio, et al.
Publicado: (2020)

Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of Different Coffee Brews Chemically Profiled through UHPLC-Q-Orbitrap HRMS
por: Castaldo, Luigi, et al.
Publicado: (2021)

Profiling of chemical constituents of Matricarla chamomilla L. by UHPLC-Q-Orbitrap-HRMS and in vivo evaluation its anti-asthmatic activity
por: Li, Qian, et al.
Publicado: (2023)

Comprehensive metabolomic profiling of osteosarcoma based on UHPLC-HRMS
por: Lv, Dongming, et al.
Publicado: (2020)

Untargeted Ultrahigh-Performance Liquid Chromatography-Hybrid Quadrupole-Orbitrap Mass Spectrometry (UHPLC-HRMS) Metabolomics Reveals Propolis Markers of Greek and Chinese Origin
por: Stavropoulou, Maria-Ioanna, et al.
Publicado: (2021)

Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of a Red Cabbage Extract Chemically Profiled through UHPLC-Q-Orbitrap HRMS
por: Izzo, Luana, et al.
Publicado: (2020)

Chemical profiling and quantification of XueBiJing injection, a systematic quality control strategy using UHPLC-Q Exactive hybrid quadrupole-orbitrap high-resolution mass spectrometry
por: Sun, Zhi, et al.
Publicado: (2017)

Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS
por: Mazaleuskaya, Liudmila L., et al.
Publicado: (2018)

Simultaneous determination of eight analytes of Fuzheng Huayu recipe in beagle dog plasma by UHPLC–Q/exactive Orbitrap HRMS and its application to toxicokinetics
por: Wang, Yu‐Lin, et al.
Publicado: (2022)

Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients
por: Zhou, Yanyan, et al.
Publicado: (2017)

Development and validation of an UHPLC-Orbitrap-HRMS method for rapid determination of endogenous L-carnitine in patients on hemodialysis/peritoneal dialysis and its application to promote rational drug use
por: Jiang, Wen-Ting, et al.
Publicado: (2022)

Biomarker discovery in galactosemia: Metabolomics with UPLC/HRMS in dried blood spots
por: Alodaib, Ahmad N., et al.
Publicado: (2023)

Identification and determination of myriocin in Isaria cicadae and its allies by LTQ-Orbitrap-HRMS
por: Cheng, Wen-ming, et al.
Publicado: (2017)

Meldonium determination in milk and meat through UHPLC-HRMS
por: Temerdashev, A., et al.
Publicado: (2020)

Establishment and validation of analytical methods for 15 hazardous drugs by UPLC-Q/Orbitrap-HRMS
por: Yu, Bo, et al.
Publicado: (2022)

Analysis of Lutein Content in Microencapsulated Marigold Flower Extract (Tagetes erecta L.) Using UHPLC-Q-Orbitrap-HRMS and Its Cytotoxicity in ARPE-19 Cells
por: Suwanklang, Pornson, et al.
Publicado: (2023)

Serum untargeted lipidomics by UHPLC-ESI-HRMS aids the biomarker discovery of colorectal adenoma
por: Zhou, Hailin, et al.
Publicado: (2022)

UHPLC-HRMS/MS on untargeted metabolomics: a case study with Copaifera (Fabaceae)
por: Antonio, Ananda da Silva, et al.
Publicado: (2021)

Association of Coronary Artery Disease and Metabolic Syndrome: Usefulness of Serum Metabolomics Approach
por: Jing, Ziwei, et al.
Publicado: (2021)

Application of the UHPLC-DIA-HRMS Method for Determination of Cheese Peptides
por: Arju, Georg, et al.
Publicado: (2020)

The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
por: Ma, Jieyao, et al.
Publicado: (2022)

Determination of Bioactive Compounds in Sequential Extracts of Chia Leaf (Salvia hispanica L.) Using UHPLC-HRMS (Q-Orbitrap) and a Global Evaluation of Antioxidant In Vitro Capacity
por: Zúñiga-López, María Carolina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_si9jbh7ackq3unrc01qohe0o2n