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Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth

Local disturbances of the microbiota are common in dogs with underlying skin conditions. Antiseptic topical products are indicated to control such superficial disorders. The objective of this study was to evaluate the performance of a daily application of pads containing Ophytrium and chlorhexidine...

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Autores principales: Gatellet, Marina, Kesteman, Roxane, Baulez, Benjamin, Pradiès, Félix, Cadot, Pierre-Marie, Dropsy, Hélène, Fiora, Pierre, Mathet, Jean-Loup, Ollivier, Elodie, Billy, Charlotte, Zemirline, Claudine, De Jaeger, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138468/
https://www.ncbi.nlm.nih.gov/pubmed/34026882
http://dx.doi.org/10.3389/fvets.2021.579074
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author Gatellet, Marina
Kesteman, Roxane
Baulez, Benjamin
Pradiès, Félix
Cadot, Pierre-Marie
Dropsy, Hélène
Fiora, Pierre
Mathet, Jean-Loup
Ollivier, Elodie
Billy, Charlotte
Zemirline, Claudine
De Jaeger, Xavier
author_facet Gatellet, Marina
Kesteman, Roxane
Baulez, Benjamin
Pradiès, Félix
Cadot, Pierre-Marie
Dropsy, Hélène
Fiora, Pierre
Mathet, Jean-Loup
Ollivier, Elodie
Billy, Charlotte
Zemirline, Claudine
De Jaeger, Xavier
author_sort Gatellet, Marina
collection PubMed
description Local disturbances of the microbiota are common in dogs with underlying skin conditions. Antiseptic topical products are indicated to control such superficial disorders. The objective of this study was to evaluate the performance of a daily application of pads containing Ophytrium and chlorhexidine digluconate 3% (DOUXO® S3 PYO Pads, Ceva Santé Animale, France) in dogs with focal bacterial and/or Malassezia overgrowth. Eighteen dogs with focal skin dysbiosis were included in the analysis of this prospective, multicentric, field study. Dogs received daily pad applications for 14 days. Bacterial and/or Malassezia counts per microscopic field and a global score of the most affected patch (0–17 scale based on extension, severity, bacterial, and Malassezia cytological scores) were assessed by a veterinarian and pruritus by the owner (Pruritus Visual Analog Scale) on days (D)0, D7, D14. Owner and veterinarian evaluations for performance and satisfaction were recorded. Eleven dogs had primarily cocci overgrowth and seven mostly Malassezia. Mean bacterial and Malassezia counts decreased after 14 days (6.9–1.1; 7.6–1.5, respectively); 88.9% of dogs achieved a ≥70% microbial decrease and had ≤2 bacteria and ≤1 Malassezia per oil field. Mean global score of the most affected patch and pruritus score significantly improved at D14, respectively, from 8.6 to 2.6 and 4.5 to 1.2 (P < 0.05 each, mean improvements of 70.4 and 71.4%, respectively). Global veterinary assessment of the protocol was satisfactory, good, or excellent in 88.9% of cases. Most owners (94.4%) considered the protocol efficacious. Using a pad containing Ophytrium and chlorhexidine digluconate 3% daily for 14 days improved the skin condition and pruritus of dogs with local dysbiosis, resulting in high satisfaction levels for both veterinarians and dog owners.
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spelling pubmed-81384682021-05-22 Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth Gatellet, Marina Kesteman, Roxane Baulez, Benjamin Pradiès, Félix Cadot, Pierre-Marie Dropsy, Hélène Fiora, Pierre Mathet, Jean-Loup Ollivier, Elodie Billy, Charlotte Zemirline, Claudine De Jaeger, Xavier Front Vet Sci Veterinary Science Local disturbances of the microbiota are common in dogs with underlying skin conditions. Antiseptic topical products are indicated to control such superficial disorders. The objective of this study was to evaluate the performance of a daily application of pads containing Ophytrium and chlorhexidine digluconate 3% (DOUXO® S3 PYO Pads, Ceva Santé Animale, France) in dogs with focal bacterial and/or Malassezia overgrowth. Eighteen dogs with focal skin dysbiosis were included in the analysis of this prospective, multicentric, field study. Dogs received daily pad applications for 14 days. Bacterial and/or Malassezia counts per microscopic field and a global score of the most affected patch (0–17 scale based on extension, severity, bacterial, and Malassezia cytological scores) were assessed by a veterinarian and pruritus by the owner (Pruritus Visual Analog Scale) on days (D)0, D7, D14. Owner and veterinarian evaluations for performance and satisfaction were recorded. Eleven dogs had primarily cocci overgrowth and seven mostly Malassezia. Mean bacterial and Malassezia counts decreased after 14 days (6.9–1.1; 7.6–1.5, respectively); 88.9% of dogs achieved a ≥70% microbial decrease and had ≤2 bacteria and ≤1 Malassezia per oil field. Mean global score of the most affected patch and pruritus score significantly improved at D14, respectively, from 8.6 to 2.6 and 4.5 to 1.2 (P < 0.05 each, mean improvements of 70.4 and 71.4%, respectively). Global veterinary assessment of the protocol was satisfactory, good, or excellent in 88.9% of cases. Most owners (94.4%) considered the protocol efficacious. Using a pad containing Ophytrium and chlorhexidine digluconate 3% daily for 14 days improved the skin condition and pruritus of dogs with local dysbiosis, resulting in high satisfaction levels for both veterinarians and dog owners. Frontiers Media S.A. 2021-05-07 /pmc/articles/PMC8138468/ /pubmed/34026882 http://dx.doi.org/10.3389/fvets.2021.579074 Text en Copyright © 2021 Gatellet, Kesteman, Baulez, Pradiès, Cadot, Dropsy, Fiora, Mathet, Ollivier, Billy, Zemirline and De Jaeger. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Gatellet, Marina
Kesteman, Roxane
Baulez, Benjamin
Pradiès, Félix
Cadot, Pierre-Marie
Dropsy, Hélène
Fiora, Pierre
Mathet, Jean-Loup
Ollivier, Elodie
Billy, Charlotte
Zemirline, Claudine
De Jaeger, Xavier
Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title_full Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title_fullStr Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title_full_unstemmed Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title_short Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or Malassezia Overgrowth
title_sort performance of daily pads containing ophytrium and chlorhexidine digluconate 3% in dogs with local cutaneous bacterial and/or malassezia overgrowth
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138468/
https://www.ncbi.nlm.nih.gov/pubmed/34026882
http://dx.doi.org/10.3389/fvets.2021.579074
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