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A20/TNFAIP3 Increases ENOS Expression in an ERK5/KLF2-Dependent Manner to Support Endothelial Cell Health in the Face of Inflammation

Rationale: Decreased expression and activity of endothelial nitric oxide synthase (eNOS) in response to inflammatory and metabolic insults is the hallmark of endothelial cell (EC) dysfunction that preludes the development of atherosclerosis and hypertension. We previously reported the atheroprotecti...

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Detalles Bibliográficos
Autores principales: Angolano, Cleide, Kaczmarek, Elzbieta, Essayagh, Sanah, Daniel, Soizic, Choi, Lynn Y., Tung, Brian, Sauvage, Gabriel, Lee, Andy, Kipper, Franciele C., Arvelo, Maria B., Moll, Herwig P., Ferran, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138474/
https://www.ncbi.nlm.nih.gov/pubmed/34026871
http://dx.doi.org/10.3389/fcvm.2021.651230