Near-infrared photoimmunotherapy targeting GPR87: Development of a humanised anti-GPR87 mAb and therapeutic efficacy on a lung cancer mouse model

BACKGROUND: GPR87 is a G-protein receptor that is specifically expressed in tumour cells, such as lung cancer, and rarely expressed in normal cells. GPR87 is a promising target for cancer therapy, but its ligand is controversial. Near-infrared photoimmunotherapy (NIR-PIT) is a novel cancer therapy i...

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Detalles Bibliográficos
Autores principales: Yasui, Hirotoshi, Nishinaga, Yuko, Taki, Shunichi, Takahashi, Kazuomi, Isobe, Yoshitaka, Shimizu, Misae, Koike, Chiaki, Taki, Tetsuro, Sakamoto, Aya, Katsumi, Keiko, Ishii, Keisuke, Sato, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138482/
https://www.ncbi.nlm.nih.gov/pubmed/33993055
http://dx.doi.org/10.1016/j.ebiom.2021.103372

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