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Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

SARS‐CoV‐2 is the coronavirus responsible for the COVID‐19 pandemic. Proteases are central to the infection process of SARS‐CoV‐2. Cleavage of the spike protein on the virus's capsid causes the conformational change that leads to membrane fusion and viral entry into the target cell. Since inhib...

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Detalles Bibliográficos
Autores principales:	Bollavaram, Keval, Leeman, Tiffanie H., Lee, Maggie W., Kulkarni, Akhil, Upshaw, Sophia G., Yang, Jiabei, Song, Hannah, Platt, Manu O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Full‐Length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138523/ https://www.ncbi.nlm.nih.gov/pubmed/33786919 http://dx.doi.org/10.1002/pro.4073

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