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Electrostatic Interaction Between NS1 and Negatively Charged Lipids Contributes to Flavivirus Replication Organelles Formation

Flavivirus replication occurs in membranous replication compartments, also known as replication organelles (ROs) derived from the host ER membrane. Our previous study showed that the non-structural (NS) protein 1 (NS1) is the essential factor for RO creation by hydrophobic insertion into the ER memb...

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Detalles Bibliográficos
Autores principales: Ci, Yali, Yang, Yang, Xu, Caimin, Qin, Cheng-Feng, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138564/
https://www.ncbi.nlm.nih.gov/pubmed/34025602
http://dx.doi.org/10.3389/fmicb.2021.641059