Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas

Thrombocytopenia in coronavirus disease-2019 (COVID-19) can be attributed to multiple factors. Most often it is disease related. It is usually mild and if severe often associated with severe COVID-19 disease. It can also be due to drugs (Remdesivir, Tocilizumab) or coinfection with other viruses. He...

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Autores principales: Adarsh, MB, Abraham, Anitha, Kavitha, P, Nandakumar, Meera M, Vaman, Raman S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138641/
https://www.ncbi.nlm.nih.gov/pubmed/34045816
http://dx.doi.org/10.5005/jp-journals-10071-23778
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author Adarsh, MB
Abraham, Anitha
Kavitha, P
Nandakumar, Meera M
Vaman, Raman S
author_facet Adarsh, MB
Abraham, Anitha
Kavitha, P
Nandakumar, Meera M
Vaman, Raman S
author_sort Adarsh, MB
collection PubMed
description Thrombocytopenia in coronavirus disease-2019 (COVID-19) can be attributed to multiple factors. Most often it is disease related. It is usually mild and if severe often associated with severe COVID-19 disease. It can also be due to drugs (Remdesivir, Tocilizumab) or coinfection with other viruses. Here we report two cases of severe thrombocytopenia in COVID-19 due to dengue coinfection. Most often the thrombocytopenia in dengue is self-resolving, and a careful “wait and watch” should suffice unlike COVID-19, where steroids can help if the cytopenia is due to cytokine storm or immune-mediated effects. HOW TO CITE THIS ARTICLE: Adarsh MB, Abraham A, Kavitha P, Nandakumar MM, Vaman RS. Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas. Indian J Crit Care Med 2021;25(4):465–466.
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spelling pubmed-81386412021-05-26 Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas Adarsh, MB Abraham, Anitha Kavitha, P Nandakumar, Meera M Vaman, Raman S Indian J Crit Care Med Case Report Thrombocytopenia in coronavirus disease-2019 (COVID-19) can be attributed to multiple factors. Most often it is disease related. It is usually mild and if severe often associated with severe COVID-19 disease. It can also be due to drugs (Remdesivir, Tocilizumab) or coinfection with other viruses. Here we report two cases of severe thrombocytopenia in COVID-19 due to dengue coinfection. Most often the thrombocytopenia in dengue is self-resolving, and a careful “wait and watch” should suffice unlike COVID-19, where steroids can help if the cytopenia is due to cytokine storm or immune-mediated effects. HOW TO CITE THIS ARTICLE: Adarsh MB, Abraham A, Kavitha P, Nandakumar MM, Vaman RS. Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas. Indian J Crit Care Med 2021;25(4):465–466. Jaypee Brothers Medical Publishers 2021-04 /pmc/articles/PMC8138641/ /pubmed/34045816 http://dx.doi.org/10.5005/jp-journals-10071-23778 Text en Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© Jaypee Brothers Medical Publishers. 2021 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Adarsh, MB
Abraham, Anitha
Kavitha, P
Nandakumar, Meera M
Vaman, Raman S
Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title_full Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title_fullStr Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title_full_unstemmed Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title_short Severe Thrombocytopenia in COVID-19: A Conundrum in Dengue-endemic Areas
title_sort severe thrombocytopenia in covid-19: a conundrum in dengue-endemic areas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138641/
https://www.ncbi.nlm.nih.gov/pubmed/34045816
http://dx.doi.org/10.5005/jp-journals-10071-23778
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