Cargando…

Inhibition of MUC1-C Increases ROS and Cell Death in Mouse Embryonic Stem Cells

BACKGROUND AND OBJECTIVES: Embryonic stem (ES) cells have the capacity to self-renew and generate all types of cells. MUC1-C, a cytoplasmic subunit of MUC1, is overexpressed in various carcinomas and mediates signaling pathways to regulate intracellular metabolic processes and gene expression involv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Jeong-A, Park, Sangkyu, Choi, Jun-Kyu, Han, Myung-Kwan, Lee, Younghee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138657/ https://www.ncbi.nlm.nih.gov/pubmed/33122470 http://dx.doi.org/10.15283/ijsc20089

Ejemplares similares

Splitomicin, a SIRT1 Inhibitor, Enhances Hematopoietic Differentiation of Mouse Embryonic Stem Cells
por: Park, Jeong-A, et al.
Publicado: (2019)

Enhancement of Transgene Expression by HDAC Inhibitors in Mouse Embryonic Stem Cells
por: Kim, Young-Eun, et al.
Publicado: (2013)

MUC1-C influences cell survival in lung adenocarcinoma Calu-3 cells after SARS-CoV-2 infection
por: Kim, Dongbum, et al.
Publicado: (2021)

Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cells
por: Park, Sangkyu, et al.
Publicado: (2017)

Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells
por: Kim, So-Yeon, et al.
Publicado: (2016)

Cremastranone-Derived Homoisoflavanes Suppress the Growth of Breast Cancer Cells via Cell Cycle Arrest and Caspase-Independent Cell Death
por: Choi, Yeram, et al.
Publicado: (2023)

HSP60 is required for stemness and proper differentiation of mouse embryonic stem cells
por: Seo, Nan-Hee, et al.
Publicado: (2018)

Chromosomal Modification in Human Embryonic Stem Cells Cultured in a Feeder-Free Condition after Single Cell Dissociation using Accutase
por: Kim, Young-Eun, et al.
Publicado: (2012)

Loss of βPix Causes Defects in Early Embryonic Development, and Cell Spreading and Platelet-Derived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts
por: Kang, TaeIn, et al.
Publicado: (2019)

Changes in the phosphorylation of nucleotide metabolism-associated proteins by leukemia inhibitory factor in mouse embryonic stem cells
por: Song, Hwa-Ryung, et al.
Publicado: (2021)

Cell-Permeable Oct4 Gene Delivery Enhances Stem Cell-like Properties of Mouse Embryonic Fibroblasts
por: Choi, Da Hyeon, et al.
Publicado: (2021)

Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage
por: Park, Sangkyu, et al.
Publicado: (2019)

Characterization of Bovine NANOG5′-flanking Region during Differentiation of Mouse Embryonic Stem Cells
por: Jang, Hye-Jeong, et al.
Publicado: (2015)

Targeting TM4SF5 with anti-TM4SF5 monoclonal antibody suppresses the growth and motility of human pancreatic cancer cells
por: Park, Sangkyu, et al.
Publicado: (2020)

Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis
por: Shin, Ha-Eun, et al.
Publicado: (2022)

Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection
por: Park, Byoung Kwon, et al.
Publicado: (2021)

Erratum to "Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis" [Biomol. Ther. 30 (2022) 576-584]
por: Shin, Ha-Eun, et al.
Publicado: (2023)

Effects of Feeder Cell Types on Culture of Mouse Embryonic Stem Cell In Vitro
por: Park, Yun-Gwi, et al.
Publicado: (2015)

Visfatin induces MUC8 and MUC5B expression via p38 MAPK/ROS/NF-κB in human airway epithelial cells
por: Song, Si-Youn, et al.
Publicado: (2014)

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model
por: Park, Sangkyu, et al.
Publicado: (2018)

Multi-layered global gene regulation in mouse embryonic stem cells
por: Beck, Samuel, et al.
Publicado: (2014)

Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells
por: Kang, Seok-Jin, et al.
Publicado: (2014)

Noggin Over-Expressing Mouse Embryonic Fibroblasts and MS5 Stromal Cells Enhance Directed Differentiation of Dopaminergic Neurons from Human Embryonic Stem Cells
por: Lim, Mi-Sun, et al.
Publicado: (2015)

Chromosome Instability in mouse Embryonic Stem Cells
por: Gaztelumendi, Nerea, et al.
Publicado: (2014)

Is mouse embryonic stem cell technology obsolete?
por: Skarnes, William C
Publicado: (2015)

LIF signal in mouse embryonic stem cells
por: Ohtsuka, Satoshi, et al.
Publicado: (2015)

In Vitro Derivation of Functional Sertoli-Like Cells from Mouse Embryonic Stem Cells
por: Seol, Dong-Won, et al.
Publicado: (2018)

Cancer stem cell induction from mouse embryonic stem cells
por: Seno, Akimasa, et al.
Publicado: (2019)

Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells
por: Xu, Chenze, et al.
Publicado: (2019)

Arid4b alters cell cycle and cell death dynamics during mouse embryonic stem cell differentiation
por: GÜVEN, Gözde, et al.
Publicado: (2021)

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts
por: Krais, Annette M., et al.
Publicado: (2015)

Regenerative potential of mouse embryonic stem cell-derived PDGFRα(+) cardiac lineage committed cells in infarcted myocardium
por: Hong, Seon Pyo, et al.
Publicado: (2019)

SIRT1 Knockdown Enhances the Differentiation of Human Embryonic Stem Cells into Pancreatic β Cells
por: Seo, Nan-Hee, et al.
Publicado: (2019)

Arid3a regulates mesoderm differentiation in mouse embryonic stem cells
por: Popowski, Melissa, et al.
Publicado: (2017)

Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells
por: Kučera, Jan, et al.
Publicado: (2017)

Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
por: Kim, Chuna, et al.
Publicado: (2021)

Necroptosis Is a Mechanism of Death in Mouse Induced Hepatocyte-Like Cells Reprogrammed from Mouse Embryonic Fibroblasts
por: Lee, Yun-Suk, et al.
Publicado: (2018)

Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells
por: Rhee, Catherine, et al.
Publicado: (2017)

Epigenetic Changes of Lentiviral Transgenes in Porcine Stem Cells Derived from Embryonic Origin
por: Choi, Kwang-Hwan, et al.
Publicado: (2013)

AIMP3 depletion causes genome instability and loss of stemness in mouse embryonic stem cells
por: Kim, Sun Mi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7m66nth2h58mdt3c29hstjmv95