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Insulin-like growth factor-2 regulates basal retinal insulin receptor activity

The retinal insulin receptor (IR) exhibits basal kinase activity equivalent to that of the liver of fed animals, but unlike the liver, does not fluctuate with feeding and fasting; it also declines rapidly after the onset of insulin-deficient diabetes. The ligand(s) that determine basal IR activity i...

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Detalles Bibliográficos
Autores principales: Zolov, Sergey N., Imai, Hisanori, Losiewicz, Mandy K., Singh, Ravi S.J., Fort, Patrice E., Gardner, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138762/
https://www.ncbi.nlm.nih.gov/pubmed/33915127
http://dx.doi.org/10.1016/j.jbc.2021.100712

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