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Insulin-like growth factor-2 regulates basal retinal insulin receptor activity
The retinal insulin receptor (IR) exhibits basal kinase activity equivalent to that of the liver of fed animals, but unlike the liver, does not fluctuate with feeding and fasting; it also declines rapidly after the onset of insulin-deficient diabetes. The ligand(s) that determine basal IR activity i...
Autores principales: | Zolov, Sergey N., Imai, Hisanori, Losiewicz, Mandy K., Singh, Ravi S.J., Fort, Patrice E., Gardner, Thomas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138762/ https://www.ncbi.nlm.nih.gov/pubmed/33915127 http://dx.doi.org/10.1016/j.jbc.2021.100712 |
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