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Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules

T helper (Th) 17 cells protect from infections and are pathogenic in autoimmunity. While human Th17 cell differentiation has been defined, the global and stepwise transcriptional changes accompanying this process remain uncharacterized. Herein, by performing transcriptome analysis of human Th17 cell...

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Detalles Bibliográficos
Autores principales: Capone, Alessia, Naro, Chiara, Bianco, Manuela, De Bardi, Marco, Noël, Floriane, Macchi, Paolo, Battistini, Luca, Soumelis, Vassili, Volpe, Elisabetta, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138776/
https://www.ncbi.nlm.nih.gov/pubmed/34036250
http://dx.doi.org/10.1016/j.isci.2021.102492