Detection of somatic structural variants from short-read next-generation sequencing data

Somatic structural variants (SVs), which are variants that typically impact >50 nucleotides, play a significant role in cancer development and evolution but are notoriously more difficult to detect than small variants from short-read next-generation sequencing (NGS) data. This is due to a combina...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Tingting, Hayes, Vanessa M, Chan, Eva K F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138798/
https://www.ncbi.nlm.nih.gov/pubmed/32379294
http://dx.doi.org/10.1093/bib/bbaa056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138798/
https://www.ncbi.nlm.nih.gov/pubmed/32379294
http://dx.doi.org/10.1093/bib/bbaa056

Ejemplares similares