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Loss of H3K27 trimethylation is frequent in IDH1-R132H but not in non-canonical IDH1/2 mutated and 1p/19q codeleted oligodendroglioma: a Japanese cohort study

Oligodendrogliomas are defined by mutation in isocitrate dehydrogenase (NADP(+)) (IDH)1/2 genes and chromosome 1p/19q codeletion. World Health Organisation diagnosis endorses testing for 1p/19q codeletion to distinguish IDH mutant (Mut) oligodendrogliomas from astrocytomas because these gliomas requ...

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Detalles Bibliográficos
Autores principales: Habiba, Umma, Sugino, Hirokazu, Yordanova, Roumyana, Ise, Koki, Tanei, Zen-ichi, Ishida, Yusuke, Tanikawa, Satoshi, Terasaka, Shunsuke, Sato, Ken-ichi, Kamoshima, Yuuta, Katoh, Masahiko, Nagane, Motoo, Shibahara, Junji, Tsuda, Masumi, Tanaka, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138926/
https://www.ncbi.nlm.nih.gov/pubmed/34020723
http://dx.doi.org/10.1186/s40478-021-01194-7

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