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Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration
BACKGROUND: The endoglycosidase heparanase which degrades heparan sulfate proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders. However, the function and underlying mechanism of heparanase in acute pancreatitis remain poorly understood. Here, we investigated the interp...
Autores principales: | Lei, Yuanyuan, Tang, Li, Liu, Shuang, Hu, Shiping, Wu, Lingyi, Liu, Yaojiang, Yang, Min, Huang, Shengjie, Tang, Xuefeng, Tang, Tao, Zhao, Xiaoyan, Vlodavsky, Israel, Zeng, Shuo, Tang, Bo, Yang, Shiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138927/ https://www.ncbi.nlm.nih.gov/pubmed/34016163 http://dx.doi.org/10.1186/s40168-021-01065-2 |
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