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Focused ultrasound enhances the anesthetic effects of topical lidocaine in rats
BACKGROUND: High-intensity ultrasound has been used to induce acoustic cavitation in the skin and subsequently enhances skin permeability to deliver hydrophobic topical medications including lidocaine. In contrast, instead of changing skin permeability, pulsed application of low-intensity focused ul...
Autores principales: | Kim, Hyun-Chul, Lee, Wonhye, Böhlke, Mark, Yoon, Kyungho, Yoo, Seung-Schik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138995/ https://www.ncbi.nlm.nih.gov/pubmed/34020595 http://dx.doi.org/10.1186/s12871-021-01381-y |
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