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The ketogenic diet increases Neuregulin 1 expression via elevating histone acetylation and its anti-seizure effect requires ErbB4 kinase activity

BACKGROUND: The ketogenic diet (KD)has been considered an effective treatment for epilepsy, whereas its underlying mechanisms remain obscure. We have previously reported that the KD feeding increased Neuregulin 1 (NRG1) expression in the hippocampus; disruption of NRG1 signaling by genetically delet...

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Detalles Bibliográficos
Autores principales:	Wang, Jin, Huang, Jie, Yao, Shan, Wu, Jia-Hui, Li, Hui-Bin, Gao, Feng, Wang, Ying, Huang, Guo-Bin, You, Qiang-Long, Li, Jianhua, Chen, Xiaohui, Sun, Xiang-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139023/ https://www.ncbi.nlm.nih.gov/pubmed/34020711 http://dx.doi.org/10.1186/s13578-021-00611-7

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