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Case report: surgical resection of right ventricular cardiac fibroma in an adult patient

BACKGROUND: Cardiac fibromas are rare benign cardiac neoplasms, most frequently occurring in the pediatric population; with very rare cases identified in adults. The tumors are comprised of spindled cells with myofibroblastic ultrastructural features embedded in generally collagenous and elastic str...

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Autores principales: Ikegami, Hirohisa, Lemaire, Anthony, Gowda, Subhashini, Fyfe, Billie, Ali, Mahmoud, Russo, Mark J., Lee, Leonard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139114/
https://www.ncbi.nlm.nih.gov/pubmed/34016147
http://dx.doi.org/10.1186/s13019-021-01514-x
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author Ikegami, Hirohisa
Lemaire, Anthony
Gowda, Subhashini
Fyfe, Billie
Ali, Mahmoud
Russo, Mark J.
Lee, Leonard Y.
author_facet Ikegami, Hirohisa
Lemaire, Anthony
Gowda, Subhashini
Fyfe, Billie
Ali, Mahmoud
Russo, Mark J.
Lee, Leonard Y.
author_sort Ikegami, Hirohisa
collection PubMed
description BACKGROUND: Cardiac fibromas are rare benign cardiac neoplasms, most frequently occurring in the pediatric population; with very rare cases identified in adults. The tumors are comprised of spindled cells with myofibroblastic ultrastructural features embedded in generally collagenous and elastic stroma. The tumors are intramural in the ventricles, most commonly the left ventricle. Clinical symptoms vary by location and size of tumor and some are asymptomatic. Surgical resection is curative, but rare cases require cardiac transplantation. CASE PRESENTATION: We report an asymptomatic, large, right ventricular fibroma in a 64-year-old woman. The patient underwent open incisional tumor biopsy via lower hemi-sternotomy, followed by complete tumor resection via full sternotomy a week later after confirming the tumor is benign. The tumor was resected using cardiopulmonary bypass, and the defect of right ventricular free wall was repaired using a prosthetic double-patch technique. The postoperative course was uneventful. The patient was discharged to home on day 4 post-complete tumor resection. CONCLUSION: This report expands the existing literature for better comprehension and detection of cardiac fibroma patients and also highlights the various imaging modalities, surgical management, and histological analysis.
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spelling pubmed-81391142021-05-21 Case report: surgical resection of right ventricular cardiac fibroma in an adult patient Ikegami, Hirohisa Lemaire, Anthony Gowda, Subhashini Fyfe, Billie Ali, Mahmoud Russo, Mark J. Lee, Leonard Y. J Cardiothorac Surg Case Report BACKGROUND: Cardiac fibromas are rare benign cardiac neoplasms, most frequently occurring in the pediatric population; with very rare cases identified in adults. The tumors are comprised of spindled cells with myofibroblastic ultrastructural features embedded in generally collagenous and elastic stroma. The tumors are intramural in the ventricles, most commonly the left ventricle. Clinical symptoms vary by location and size of tumor and some are asymptomatic. Surgical resection is curative, but rare cases require cardiac transplantation. CASE PRESENTATION: We report an asymptomatic, large, right ventricular fibroma in a 64-year-old woman. The patient underwent open incisional tumor biopsy via lower hemi-sternotomy, followed by complete tumor resection via full sternotomy a week later after confirming the tumor is benign. The tumor was resected using cardiopulmonary bypass, and the defect of right ventricular free wall was repaired using a prosthetic double-patch technique. The postoperative course was uneventful. The patient was discharged to home on day 4 post-complete tumor resection. CONCLUSION: This report expands the existing literature for better comprehension and detection of cardiac fibroma patients and also highlights the various imaging modalities, surgical management, and histological analysis. BioMed Central 2021-05-20 /pmc/articles/PMC8139114/ /pubmed/34016147 http://dx.doi.org/10.1186/s13019-021-01514-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Ikegami, Hirohisa
Lemaire, Anthony
Gowda, Subhashini
Fyfe, Billie
Ali, Mahmoud
Russo, Mark J.
Lee, Leonard Y.
Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title_full Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title_fullStr Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title_full_unstemmed Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title_short Case report: surgical resection of right ventricular cardiac fibroma in an adult patient
title_sort case report: surgical resection of right ventricular cardiac fibroma in an adult patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139114/
https://www.ncbi.nlm.nih.gov/pubmed/34016147
http://dx.doi.org/10.1186/s13019-021-01514-x
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