MLH1 Deficiency Down-Regulates TLR4 Expression in Sporadic Colorectal Cancer

Patients with mismatch repair (MMR)-deficient colorectal cancer (CRC) have a more favorable prognosis than patients with tumors with intact MMR. In order to obtain further insights on the reasons for this different outcome, we investigated the interplay between MMR genes and TLR4/MyD88 signaling. Th...

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Detalles Bibliográficos
Autores principales: Scarpa, Melania, Ruffolo, Cesare, Kotsafti, Andromachi, Canal, Fabio, Erroi, Francesca, Basato, Silvia, DallAgnese, Lucia, Fiorot, Alain, Pozza, Anna, Brun, Paola, Bassi, Nicol, Dei Tos, Angelo, Castoro, Carlo, Castagliuolo, Ignazio, Scarpa, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139190/
https://www.ncbi.nlm.nih.gov/pubmed/34026821
http://dx.doi.org/10.3389/fmolb.2021.624873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139190/
https://www.ncbi.nlm.nih.gov/pubmed/34026821
http://dx.doi.org/10.3389/fmolb.2021.624873

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