Cargando…

The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice

BACKGROUND: The functional characteristics of NLRP3 in the pathogenesis of coxsackievirus B3- (CVB3-) induced viral myocarditis (VMC) have not been fully elucidated, and the targeted therapeutic effect of NLRP3 or its related pathway in VMC has not been reported. METHOD: In this work, the change pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jifei, Yang, Fan, Shi, Song, Liu, Xuexiang, Qin, Fengxian, Wei, Xiaomou, Huang, Yujie, Liang, Wenwu, Miao, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139334/ https://www.ncbi.nlm.nih.gov/pubmed/34093086 http://dx.doi.org/10.1155/2021/5551578

Ejemplares similares

Protective Function of STAT3 in CVB3-Induced Myocarditis
por: Lindner, Diana, et al.
Publicado: (2012)

Identification of Cardiac CircRNAs in Mice With CVB3-Induced Myocarditis
por: Nie, Xiang, et al.
Publicado: (2022)

STAT3 Suppresses Cardiomyocytes Apoptosis in CVB3-Induced Myocarditis Via Survivin
por: Wang, Qiaoyu, et al.
Publicado: (2021)

Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis
por: Liu, Xiaoxiao, et al.
Publicado: (2022)

IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis
por: Guo, Yujie, et al.
Publicado: (2014)

Alterations of the gut microbiome and metabolic profile in CVB3-induced mice acute viral myocarditis
por: Kong, Qing, et al.
Publicado: (2023)

Direct Gene Transfer with IP-10 Mutant Ameliorates Mouse CVB3-Induced Myocarditis by Blunting Th1 Immune Responses
por: Yue, Yan, et al.
Publicado: (2011)

Inhibitor of CD147 Suppresses T Cell Activation and Recruitment in CVB3-Induced Acute Viral Myocarditis
por: Wang, Ruifang, et al.
Publicado: (2023)

A20 (TNFAIP3) Alleviates CVB3-Induced Myocarditis via Inhibiting NF-κB Signaling
por: Gui, Jun, et al.
Publicado: (2012)

Remission of CVB3-induced myocarditis with Astragaloside IV treatment requires A20 (TNFAIP3) up-regulation
por: Gui, Jun, et al.
Publicado: (2015)

Transmissible endoplasmic reticulum stress from myocardiocytes to macrophages is pivotal for the pathogenesis of CVB3-induced viral myocarditis
por: Zhang, Hui, et al.
Publicado: (2017)

Intein-mediated backbone cyclization of VP1 protein enhanced protection of CVB3-induced viral myocarditis
por: Qi, Xingmei, et al.
Publicado: (2017)

Attenuated strain of CVB3 with a mutation in the CAR-interacting region protects against both myocarditis and pancreatitis
por: Lasrado, Ninaad, et al.
Publicado: (2021)

NMR-Based Metabolomic Analysis of Sera in Mouse Models of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy
por: Kong, Qing, et al.
Publicado: (2022)

Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway
por: Liang, Wei, et al.
Publicado: (2021)

Dpep2 Emerging as a Modulator of Macrophage Inflammation Confers Protection Against CVB3-Induced Viral Myocarditis
por: Yang, Xiaoli, et al.
Publicado: (2019)

An Albumin-Binding Domain Peptide Confers Enhanced Immunoprotection Against Viral Myocarditis by CVB3 VP1 Vaccine
por: Gao, Yue, et al.
Publicado: (2021)

Macrophage-Specific Coxsackievirus and Adenovirus Receptor Deletion Enhances Macrophage M1 Polarity in CVB3-Induced Myocarditis
por: Shin, Ha-Hyeon, et al.
Publicado: (2023)

NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy
por: Kong, Qing, et al.
Publicado: (2022)

CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages
por: Wang, Yanqi, et al.
Publicado: (2023)

A Monovalent Mt10-CVB3 Vaccine Prevents CVB4-Accelerated Type 1 Diabetes in NOD Mice
por: Rasquinha, Mahima T., et al.
Publicado: (2022)

Vagus nerve plays a pivotal role in CD4+ T cell differentiation during CVB3-induced murine acute myocarditis
por: Yue-Chun, Li, et al.
Publicado: (2021)

Protein Kinase B2 (PKB2/AKT2) Is Essential for Host Protection in CVB3-Induced Acute Viral Myocarditis
por: Kim, So-Hee, et al.
Publicado: (2022)

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine
por: Hankaniemi, Minna M., et al.
Publicado: (2020)

In Vitro Model Systems of Coxsackievirus B3-Induced Myocarditis: Comparison of Commonly Used Cell Lines and Characterization of CVB3-Infected iCell(®) Cardiomyocytes
por: Kraft, Lisa, et al.
Publicado: (2021)

Galectin-9 Induced Myeloid Suppressor Cells Expand Regulatory T Cells in an IL-10-Dependent Manner in CVB3-Induced Acute Myocarditis
por: Zhang, Yingying, et al.
Publicado: (2014)

Low‐intensity pulsed ultrasound attenuates cardiac inflammation of CVB3‐induced viral myocarditis via regulation of caveolin‐1 and MAPK pathways
por: Zheng, Cheng, et al.
Publicado: (2018)

Mt10-CVB3 Vaccine Virus Protects against CVB4 Infection by Inducing Cross-Reactive, Antigen-Specific Immune Responses
por: Lasrado, Ninaad, et al.
Publicado: (2021)

Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways
por: Li, Xin, et al.
Publicado: (2019)

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreatitis
por: Zhang, Hongxia, et al.
Publicado: (2021)

Monocytic myeloid-derived suppressor cells from females, but not males, alleviate CVB3-induced myocarditis by increasing regulatory and CD4(+)IL-10(+) T cells
por: Su, Nan, et al.
Publicado: (2016)

Nicotinic Agonist Inhibits Cardiomyocyte Apoptosis in CVB3-Induced Myocarditis via α3β4-nAChR/PI3K/Akt-Dependent Survivin Upregulation
por: Li, Ping, et al.
Publicado: (2019)

Abstracts from the 13th International Conference on Cerebral Vascular Biology (CVB 2019)
Publicado: (2019)

The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers
por: Dierks, Anne, et al.
Publicado: (2022)

ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis
por: Zhang, Xincai, et al.
Publicado: (2019)

Inhibition of microRNA-15 protects H9c2 cells against CVB3-induced myocardial injury by targeting NLRX1 to regulate the NLRP3 inflammasome
por: Tong, Ru, et al.
Publicado: (2020)

SNAP47 Interacts with ATG14 to Promote VP1 Conjugation and CVB3 Propagation
por: Xiang, Pinhao, et al.
Publicado: (2021)

TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1
por: Yi, Lu, et al.
Publicado: (2022)

The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells
por: Chang, Huan, et al.
Publicado: (2017)

Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells
por: Zhu, Hengshan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n8aiph2sqi3okeq77g20ulqc6s