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Tailored Pharmacokinetic model to predict drug trapping in long-term anesthesia
INTRODUCTION: In long-term induced general anesthesia cases such as those uniquely defined by the ongoing Covid-19 pandemic context, the clearance of hypnotic and analgesic drugs from the body follows anomalous diffusion with afferent drug trapping and escape rates in heterogeneous tissues. Evidence...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139433/ https://www.ncbi.nlm.nih.gov/pubmed/34484823 http://dx.doi.org/10.1016/j.jare.2021.04.004 |