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Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study

We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease an...

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Autores principales: Freidle, Malin, Johansson, Hanna, Lebedev, Alexander V., Ekman, Urban, Lövdén, Martin, Franzén, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139474/
https://www.ncbi.nlm.nih.gov/pubmed/34019565
http://dx.doi.org/10.1371/journal.pone.0251849
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author Freidle, Malin
Johansson, Hanna
Lebedev, Alexander V.
Ekman, Urban
Lövdén, Martin
Franzén, Erika
author_facet Freidle, Malin
Johansson, Hanna
Lebedev, Alexander V.
Ekman, Urban
Lövdén, Martin
Franzén, Erika
author_sort Freidle, Malin
collection PubMed
description We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease and 12 healthy individuals, all ≥ 60 years of age, were included. A serial reaction time task was used as a measure of implicit sequence learning and a similar task but with the addition of a simple counting task, was used as a measure of dual task ability. We have present thorough descriptive statistics of the data but we have refrained from any inferential statistics due to the small sample size. All participants understood the task instructions and the difficulty level of both tasks was deemed acceptable. There were indications of task fatigue that demand careful choices for how best to analyse the data from such tasks in future trials. Ceiling effects were present in several accuracy outcomes, but not in the reaction time outcomes. Overall, we found both tasks to be feasible to use in samples of individuals with mild to moderate Parkinson’s disease and healthy older individuals.
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spelling pubmed-81394742021-06-02 Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study Freidle, Malin Johansson, Hanna Lebedev, Alexander V. Ekman, Urban Lövdén, Martin Franzén, Erika PLoS One Research Article We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease and 12 healthy individuals, all ≥ 60 years of age, were included. A serial reaction time task was used as a measure of implicit sequence learning and a similar task but with the addition of a simple counting task, was used as a measure of dual task ability. We have present thorough descriptive statistics of the data but we have refrained from any inferential statistics due to the small sample size. All participants understood the task instructions and the difficulty level of both tasks was deemed acceptable. There were indications of task fatigue that demand careful choices for how best to analyse the data from such tasks in future trials. Ceiling effects were present in several accuracy outcomes, but not in the reaction time outcomes. Overall, we found both tasks to be feasible to use in samples of individuals with mild to moderate Parkinson’s disease and healthy older individuals. Public Library of Science 2021-05-21 /pmc/articles/PMC8139474/ /pubmed/34019565 http://dx.doi.org/10.1371/journal.pone.0251849 Text en © 2021 Freidle et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Freidle, Malin
Johansson, Hanna
Lebedev, Alexander V.
Ekman, Urban
Lövdén, Martin
Franzén, Erika
Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title_full Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title_fullStr Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title_full_unstemmed Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title_short Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
title_sort measuring implicit sequence learning and dual task ability in mild to moderate parkinson´s disease: a feasibility study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139474/
https://www.ncbi.nlm.nih.gov/pubmed/34019565
http://dx.doi.org/10.1371/journal.pone.0251849
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