Cargando…
Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study
We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease an...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139474/ https://www.ncbi.nlm.nih.gov/pubmed/34019565 http://dx.doi.org/10.1371/journal.pone.0251849 |
_version_ | 1783696016080371712 |
---|---|
author | Freidle, Malin Johansson, Hanna Lebedev, Alexander V. Ekman, Urban Lövdén, Martin Franzén, Erika |
author_facet | Freidle, Malin Johansson, Hanna Lebedev, Alexander V. Ekman, Urban Lövdén, Martin Franzén, Erika |
author_sort | Freidle, Malin |
collection | PubMed |
description | We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease and 12 healthy individuals, all ≥ 60 years of age, were included. A serial reaction time task was used as a measure of implicit sequence learning and a similar task but with the addition of a simple counting task, was used as a measure of dual task ability. We have present thorough descriptive statistics of the data but we have refrained from any inferential statistics due to the small sample size. All participants understood the task instructions and the difficulty level of both tasks was deemed acceptable. There were indications of task fatigue that demand careful choices for how best to analyse the data from such tasks in future trials. Ceiling effects were present in several accuracy outcomes, but not in the reaction time outcomes. Overall, we found both tasks to be feasible to use in samples of individuals with mild to moderate Parkinson’s disease and healthy older individuals. |
format | Online Article Text |
id | pubmed-8139474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-81394742021-06-02 Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study Freidle, Malin Johansson, Hanna Lebedev, Alexander V. Ekman, Urban Lövdén, Martin Franzén, Erika PLoS One Research Article We investigated the feasibility aspects of two choice reaction time tasks designed to assess implicit sequence learning and dual task ability in individuals with mild to moderate Parkinson’s disease in comparison to healthy individuals. Twelve individuals with mild to moderate Parkinson’s disease and 12 healthy individuals, all ≥ 60 years of age, were included. A serial reaction time task was used as a measure of implicit sequence learning and a similar task but with the addition of a simple counting task, was used as a measure of dual task ability. We have present thorough descriptive statistics of the data but we have refrained from any inferential statistics due to the small sample size. All participants understood the task instructions and the difficulty level of both tasks was deemed acceptable. There were indications of task fatigue that demand careful choices for how best to analyse the data from such tasks in future trials. Ceiling effects were present in several accuracy outcomes, but not in the reaction time outcomes. Overall, we found both tasks to be feasible to use in samples of individuals with mild to moderate Parkinson’s disease and healthy older individuals. Public Library of Science 2021-05-21 /pmc/articles/PMC8139474/ /pubmed/34019565 http://dx.doi.org/10.1371/journal.pone.0251849 Text en © 2021 Freidle et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Freidle, Malin Johansson, Hanna Lebedev, Alexander V. Ekman, Urban Lövdén, Martin Franzén, Erika Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title | Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title_full | Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title_fullStr | Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title_full_unstemmed | Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title_short | Measuring implicit sequence learning and dual task ability in mild to moderate Parkinson´s disease: A feasibility study |
title_sort | measuring implicit sequence learning and dual task ability in mild to moderate parkinson´s disease: a feasibility study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139474/ https://www.ncbi.nlm.nih.gov/pubmed/34019565 http://dx.doi.org/10.1371/journal.pone.0251849 |
work_keys_str_mv | AT freidlemalin measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy AT johanssonhanna measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy AT lebedevalexanderv measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy AT ekmanurban measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy AT lovdenmartin measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy AT franzenerika measuringimplicitsequencelearninganddualtaskabilityinmildtomoderateparkinsonsdiseaseafeasibilitystudy |