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NMDA receptor inhibition increases, synchronizes, and stabilizes the collective pancreatic beta cell activity: Insights through multilayer network analysis
NMDA receptors promote repolarization in pancreatic beta cells and thereby reduce glucose-stimulated insulin secretion. Therefore, NMDA receptors are a potential therapeutic target for diabetes. While the mechanism of NMDA receptor inhibition in beta cells is rather well understood at the molecular...
Autores principales: | Šterk, Marko, Križančić Bombek, Lidija, Skelin Klemen, Maša, Slak Rupnik, Marjan, Marhl, Marko, Stožer, Andraž, Gosak, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139480/ https://www.ncbi.nlm.nih.gov/pubmed/33974632 http://dx.doi.org/10.1371/journal.pcbi.1009002 |
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