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Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy

Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor acc...

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Autores principales: Han, Moo Jae, Yang, Seung Woo, Bae, Sang Il, Moon, Young Min, Jeon, Wan, Choi, Chul Won, Park, Sung Kwang, Kim, Jin Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139496/
https://www.ncbi.nlm.nih.gov/pubmed/34019553
http://dx.doi.org/10.1371/journal.pone.0251441
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author Han, Moo Jae
Yang, Seung Woo
Bae, Sang Il
Moon, Young Min
Jeon, Wan
Choi, Chul Won
Park, Sung Kwang
Kim, Jin Young
author_facet Han, Moo Jae
Yang, Seung Woo
Bae, Sang Il
Moon, Young Min
Jeon, Wan
Choi, Chul Won
Park, Sung Kwang
Kim, Jin Young
author_sort Han, Moo Jae
collection PubMed
description Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (–0.074 cm) and 0.051 cm (–0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R(50). Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.
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spelling pubmed-81394962021-06-02 Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy Han, Moo Jae Yang, Seung Woo Bae, Sang Il Moon, Young Min Jeon, Wan Choi, Chul Won Park, Sung Kwang Kim, Jin Young PLoS One Research Article Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (–0.074 cm) and 0.051 cm (–0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R(50). Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials. Public Library of Science 2021-05-21 /pmc/articles/PMC8139496/ /pubmed/34019553 http://dx.doi.org/10.1371/journal.pone.0251441 Text en © 2021 Han et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Han, Moo Jae
Yang, Seung Woo
Bae, Sang Il
Moon, Young Min
Jeon, Wan
Choi, Chul Won
Park, Sung Kwang
Kim, Jin Young
Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title_full Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title_fullStr Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title_full_unstemmed Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title_short Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
title_sort evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8139496/
https://www.ncbi.nlm.nih.gov/pubmed/34019553
http://dx.doi.org/10.1371/journal.pone.0251441
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